{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T03:28:12Z","timestamp":1790220492629,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,1,11]],"date-time":"2021-01-11T00:00:00Z","timestamp":1610323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pemphigus Vulgaris (PV) is a severe autoimmune blistering disease which may affect the patient's health\u2010related quality of life (HR\u2010QoL) and mood even during quiescent disease activity. We sought to evaluate HR\u2010QoL, quality of sleep (QoS), anxiety and depression in oropharyngeal PV patients (OPV) in complete clinical remission on or off therapy (CCR\u2010on, CCR\u2010off).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Thirty OPV patients and 30 healthy controls were enrolled. The Short Form 36 Health Survey Questionnaire (SF\u201036), Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Hamilton Rating Scale for Depression (HAM\u2010D) and Hamilton Rating Scale for Anxiety (HAM\u2010A) were administered. Descriptive statistics, including the Mann\u2010Whitney\n                      <jats:italic>U<\/jats:italic>\n                      test and hierarchical multiple linear regression analysis, were used.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The OPV patients had statistically lower scores in the majority of items of the SF\u201036 and higher scores in the PSQI, HAM\u2010A and HAM\u2010D than the healthy controls (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.004;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001; and\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001 respectively). Nine (30%) of the OPV patients were poor sleepers (PSQI\u00a0&gt;\u00a05) with higher scores in the SF\u201036, HAM\u2010A and HAM\u2010D compared with the good sleepers (PSQI\u00a0&lt;\u00a05). No statistically significant difference was detected in the OPV group when comparing patients in CCR\u2010on and CCR\u2010off, or in consideration of the cumulative time of the disease duration.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>HR\u2010QoL of OPV patients can be impaired even over periods of relatively well\u2010being, therefore, clinicians should monitor periodically their HR\u2010QoL, QoS and psychological profile in order to guide treatments also toward improving their HR\u2010QoL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.13150","type":"journal-article","created":{"date-parts":[[2020,12,13]],"date-time":"2020-12-13T12:44:58Z","timestamp":1607863498000},"page":"510-519","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["The health\u2010related quality of life and psychological profile in patients with oropharyngeal Pemphigus Vulgaris in complete clinical remission: A case\u2010control study"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0739-5650","authenticated-orcid":false,"given":"Elena","family":"Calabria","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Reproductive and Odontostomatological Sciences Federico II University of Naples Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3784-4229","authenticated-orcid":false,"given":"Daniela","family":"Adamo","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive and Odontostomatological Sciences Federico II University of Naples Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4468-5083","authenticated-orcid":false,"given":"Stefania","family":"Leuci","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive and Odontostomatological Sciences Federico II University of Naples Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Pecoraro","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive and Odontostomatological Sciences Federico II University of Naples Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0030-3621","authenticated-orcid":false,"given":"Noemi","family":"Coppola","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive and Odontostomatological Sciences Federico II University of Naples Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Aria","sequence":"additional","affiliation":[{"name":"Department of Economics and Statistics Federico II University of Naples Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele D.","family":"Mignogna","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive and Odontostomatological Sciences Federico II University of Naples Naples 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