{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:00:34Z","timestamp":1787065234067,"version":"build-2736575974"},"reference-count":50,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T00:00:00Z","timestamp":1618444800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the prevalence of oral mucosal lesions in patients with Pemphigus Vulgaris.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Observational studies reporting the prevalence of oral lesions in pemphigus vulgaris patients, without restriction to language and year of publication, were selected in a two\u2010phase process. Search strategies were applied to PubMed, Scopus, Livivo, Web of Science, LILACS, Google Scholar, and OpenGrey databases. Articles assessing the prevalence of oral lesions in patients with conditions other than pemphigus vulgaris were excluded. Risk of bias analysis was performed using the Joanna Briggs Institute's Critical Appraisal Checklist for Studies Reporting Prevalence Data. Synthesis of results was calculated by the software R Statistics version 4.0.2 (The R Foundation). Confidence in cumulative evidence was assessed with the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From 1957 studies identified, 40 were included in qualitative synthesis and 38 in meta\u2010analyses. The pooled prevalence of patients with oral lesions solely or concurrent with other mucocutaneous lesions was 90.3%. The prevalence of patients with exclusive oral mucosal lesions was 50.8%. Risk of bias was considered low, and the certainty of evidence was very low.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Oral lesions were present in approximately nine out of 10 patients with pemphigus vulgaris. The oral mucosa was the most common site of disease onset. Further longitudinal studies are urged to assess the prevalence of oral lesions at different disease stages.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.13167","type":"journal-article","created":{"date-parts":[[2021,3,13]],"date-time":"2021-03-13T11:41:41Z","timestamp":1615635701000},"page":"750-757","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Prevalence of oral mucosal lesions in patients with pemphigus vulgaris: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0158-5085","authenticated-orcid":false,"given":"Elis \u00c2ngela","family":"Batistella","sequence":"first","affiliation":[{"name":"Postgraduate Program in Dentistry Federal University of Santa Catarina Florianopolis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rayssa","family":"Sabino da Silva","sequence":"additional","affiliation":[{"name":"Dentistry School Health Sciences Center Federal University of Santa Catarina Florianopolis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8516-8771","authenticated-orcid":false,"given":"Elena Riet Correa","family":"Rivero","sequence":"additional","affiliation":[{"name":"Department of Pathology Health Sciences Center Federal University of Santa Catarina Florianopolis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina Am\u00e1lia Barcellos","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Morphological Sciences Biological Sciences Center Federal University of Santa Catarina Florianopolis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,4,15]]},"reference":[{"key":"e_1_2_13_2_1","first-page":"119","article-title":"Clinical and demographic characteristics of pemphigus vulgaris patients","volume":"26","author":"Altun E","year":"2018","journal-title":"Acta Dermatovenerol Croat"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12847"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.13059"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.13052"},{"key":"e_1_2_13_6_1","first-page":"181","article-title":"Epidemiology of pemphigus in Turkey: one\u2010year. 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