{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:10:04Z","timestamp":1791317404562,"version":"4.3.1"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T00:00:00Z","timestamp":1673222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>In this systematic review, we aimed to evaluate the clinicopathological and prognosis data of patients with salivary gland myoepithelial carcinoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>MEDLINE\/PubMed, Scopus, and Embase search was performed with the keywords \u201cmyoepithelial carcinoma\u201d \u201cmalignant myoepithelioma,\u201d and \u201csalivary glands.\u201d Primary salivary glands myoepithelial carcinoma that fulfilled the World Health Organization diagnostic criteria were included. The Joanna Briggs Institute tool was used to assess the risk of bias.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Forty\u2010three studies (71 patients) met the inclusion criteria. The patients showed a mean age of 56.4\u2009\u00b1\u200919.6\u2009years with no sex predilection. The parotid was the most affected gland (49.3%). The tumor presented as an asymptomatic (65.1%) mass (84%). The most common histological findings were the presence of clear tumor cells (39.7%) and multinodular growth patterns (60.7%). Multivariate analysis showed plasmacytoid cell type (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.010) and solid growth pattern (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.003) were related to decreased disease\u2010free survival. Surgery alone was the most used treatment (53.5%). Patients with a combination of treatments showed a longer disease\u2010free survival (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.049). The 2\u2010year and 5\u2010year overall survival rates were 67.5% and 46.1%, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Salivary gland myoepithelial carcinoma showed no sex predilection, with a higher incidence in the parotid gland. Cell type, growth pattern, and treatment type may be related to a lower disease\u2010free survival. Overall, salivary gland myoepithelial carcinoma presented low recurrence and metastasis rates.<\/jats:p>\n                    <jats:p>Registration and protocol: This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses (PRISMA) 2020 checklist and registered in the International Prospective Register of Systematic Reviews (PROSPERO) database (CRD42022311512).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.13395","type":"journal-article","created":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T02:48:15Z","timestamp":1670813295000},"page":"101-108","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Clinicopathological and survival profile of patients with salivary gland myoepithelial carcinoma: A systematic review"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3464-8879","authenticated-orcid":false,"given":"Luccas","family":"Lavareze","sequence":"first","affiliation":[{"name":"Department of Pathology, School of Medical Sciences State University of Campinas (UNICAMP)  S\u00e3o Paulo Brazil"},{"name":"Department of Oral Diagnosis, Piracicaba Dental School State University of Campinas (UNICAMP)  Piracicaba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9015-6831","authenticated-orcid":false,"given":"Jo\u00e3o Figueira","family":"Scarini","sequence":"additional","affiliation":[{"name":"Department of Pathology, School of Medical Sciences State University of Campinas (UNICAMP)  S\u00e3o Paulo Brazil"},{"name":"Department of Oral Diagnosis, Piracicaba Dental School State University of Campinas (UNICAMP)  Piracicaba 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