{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T02:59:59Z","timestamp":1775012399809,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T00:00:00Z","timestamp":1678665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The increase of the incidence of human papillomavirus dependent oropharyngeal squamous cell carcinoma is alarming, although we have greatly progressed in the classification and staging of this disease. We now know that human papillomavirus related oropharyngeal squamous cell carcinoma is a sub\u2010type of head and neck squamous cell carcinoma with favourable prognosis and good response to therapy that needs a proper system of classification and staging. Thus, in routine practice it is essential to test patients for the presence of human papillomavirus. The most popular technique to assess human papillomavirus status is immunohistochemistry on biopsy samples with p16, which is an excellent surrogate for high\u2010risk human papillomavirus infection. Another highly sensitive and specific tissue\u2010based technique for the detection of human papillomavirus is RNAscope In situ hybridization that has a prohibitive cost, limiting its use in routine practice. Radiomics is an artificial intelligence based non\u2010invasive method of computational analysis of computed tomography, magnetic resonance imaging, positron emission tomography, and ultrasound images.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this review, we summarise the last findings of radiomics applied to human papillomavirus associated oropharyngeal squamous cell carcinoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A growing body of evidence suggest that radiomics is able to characterise and detect early relapse after treatment, and enable development of tailored therapy of human papillomavirus positive oropharyngeal squamous cell carcinoma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.13419","type":"journal-article","created":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T05:34:55Z","timestamp":1677476095000},"page":"300-304","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["<scp>Human papilomaviru<\/scp>\n                    \u2010related oropharyngeal squamous cell carcinoma and radiomics: A new era?"],"prefix":"10.1111","volume":"52","author":[{"given":"Elisabetta","family":"Caprini","sequence":"first","affiliation":[{"name":"Anatomia Patologica Istituto Dermopatico dell'Immacolata IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giampaolo","family":"D'Agnese","sequence":"additional","affiliation":[{"name":"Information Technology Istituto Dermopatico dell'immacolata IDI\u2010IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter A.","family":"Brennan","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Queen Alexandra Hospital  Portsmouth UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siavash","family":"Rahimi","sequence":"additional","affiliation":[{"name":"Anatomia Patologica Istituto Dermopatico dell'Immacolata IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,3,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25516"},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1007\/978-1-4419-1472-9","volume-title":"Epidemiology, pathogenesis, and prevention of head and neck cancer","author":"Olshan AF","year":"2010"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70017-6"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.101"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.07.055"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1158\/1541\u20107786.MCR\u201021\u20100443"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/v13071326"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.36.4596"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.61.6995"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6833a3"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008\u20105472.CAN\u201016\u20100633"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055\u20109965.EPI\u201019\u20100038"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djn025"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23356"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2003.008656"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/92.9.709"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/503330a"},{"key":"e_1_2_7_19_1","first-page":"299","article-title":"HPV in oropharyngeal cancer: the basics to know in clinical practice","volume":"34","author":"Elrefaey S","year":"2014","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.2015.04.140301"},{"key":"e_1_2_7_21_1","first-page":"812","article-title":"The role of HPV status in recurrent\/metastatic squamous cell carcinoma of the head and neck","volume":"12","author":"Misiukiewicz K","year":"2014","journal-title":"Clin Adv Hematol Oncol"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.53.5633"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416\u2010019\u20100414\u20109"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12956"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/jclinpath\u20102020\u2010206686"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms5006"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2015151169"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2011.11.036"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/61\/13\/R150"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.118.222893"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41199\u2010020\u201000053\u20107"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2021.102263"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2017.06.002"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20170498"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2019.06.034"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/mp.13977"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0222509"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201061297\u20104"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330\u2010020\u201006962\u2010y"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14071674"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tranon.2020.100906"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13225689"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctro.2021.03.002"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.26979"}],"container-title":["Journal of Oral Pathology &amp; Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jop.13419","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jop.13419","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jop.13419","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T11:06:31Z","timestamp":1692702391000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jop.13419"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,13]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1111\/jop.13419"],"URL":"https:\/\/doi.org\/10.1111\/jop.13419","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/JOP.13419\/v1\/decision1","asserted-by":"object"}]},"ISSN":["0904-2512","1600-0714"],"issn-type":[{"value":"0904-2512","type":"print"},{"value":"1600-0714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,13]]},"assertion":[{"value":"2022-10-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}