{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T13:27:22Z","timestamp":1791638842935,"version":"4.3.4"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T00:00:00Z","timestamp":1684886400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Unicystic ameloblastoma is an encapsulated odontogenic neoplasm with a single cyst cavity. The conservative or aggressive surgical approaches used to treat the tumor directly affect recurrence rates. However, there is a lack of a standard protocol that can guide its management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>We retrospectively reviewed the clinicopathological findings and therapeutical procedures of 12 unicystic ameloblastoma cases treated by the same surgeon during the past 20\u2009years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All cases of unicystic ameloblastoma diagnosed by biopsy and treated by the same surgeon between 2002 and 2022 were reviewed. Eligibility criteria were patients with completely filled\u2010out charts containing the follow\u2010up period and confirmation of the diagnoses based on the microscopic findings of the whole excised specimens. Data collected were categorized into clinical, radiographic, histological, surgical, and recurrence aspects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was a female predilection (2:1), and ages ranged between 18 and 61\u2009years (mean: 27.25, \u00b112.45). Almost all (92%) affected the posterior mandible. Radiographically, the mean length of the lesions was 46.14\u2009mm\u2009\u00b1\u200914.28\u2009mm which 92% were unilocular and 8.3% multilocular. Root resorption (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20097, 58%), tooth displacement (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20099, 75%), and cortical perforation (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20095, 42%) were also observed. The mural histological subtype corresponded to 9 (75%) of the cases. The same conservative protocol was performed in all cases. The follow\u2010up period ranged between 12 and 240\u2009months (~62\u2009\u00b1\u200965) and recurrence occurred in only one patient (8%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings suggest a conservative approach should be the first option for unicystic ameloblastoma treatment, even for those with mural proliferation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.13453","type":"journal-article","created":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T14:01:00Z","timestamp":1684936860000},"page":"654-659","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["A conservative approach for unicystic ameloblastoma: Retrospective clinic\u2010pathologic analysis of 12 cases"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2615-2948","authenticated-orcid":false,"given":"Fl\u00e1via","family":"Leite\u2010Lima","sequence":"first","affiliation":[{"name":"Department of Oral Surgery and Pathology, School of Dentistry Universidade Federal de Minas Gerais (UFMG)  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta Rayra","family":"Martins\u2010Chaves","sequence":"additional","affiliation":[{"name":"Medical School, Faculdade Ci\u00eancias M\u00e9dicas de Minas Gerais  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6657-4547","authenticated-orcid":false,"given":"Felipe Paiva","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Pathology, School of Dentistry Universidade Federal de Minas Gerais (UFMG)  Belo Horizonte Brazil"},{"name":"Universidade Federal de Minas Gerais (UFMG)  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"Brennan","sequence":"additional","affiliation":[{"name":"Department of Oral &amp; Maxillofacial Surgery Queen Alexandra Hospital  Portsmouth UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wagner Henriques","family":"de Castro","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Pathology, School of Dentistry Universidade Federal de Minas Gerais (UFMG)  Belo Horizonte Brazil"},{"name":"Universidade Federal de Minas Gerais (UFMG)  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo Santiago","family":"Gomez","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Pathology, School of Dentistry Universidade Federal de Minas Gerais (UFMG)  Belo Horizonte Brazil"},{"name":"Medical School, Faculdade Ci\u00eancias M\u00e9dicas de Minas Gerais  Belo Horizonte Brazil"},{"name":"Universidade Federal de Minas Gerais (UFMG)  Belo Horizonte Brazil"},{"name":"Department of Oral &amp; Maxillofacial Surgery Queen Alexandra Hospital  Portsmouth UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197711)40:5<2278::AID-CNCR2820400539>3.0.CO;2-L"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.13155"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2021.07.022"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/jhnps.jhnps_1_20"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/joms.2003.50002"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12663-016-0987-2"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976-237X.132305"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2019.04.008"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12646"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12663-022-01694-6"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12740"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.14477"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034518798810"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2001.113110"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2005.11.032"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2006.02.013"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-011-0391-7"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.13228"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2021.07.008"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jobcr.2017.08.007"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2009.11.022"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12663-010-0060-5"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijms.61500"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.5794\/jjoms.64.347"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-015-3631-8"}],"container-title":["Journal of Oral Pathology &amp; 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