{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T10:04:26Z","timestamp":1787306666632,"version":"build-2736575974"},"reference-count":49,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,9,29]],"date-time":"2024-09-29T00:00:00Z","timestamp":1727568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Diabetes mellitus (DM) has been associated with salivary disorders such as xerostomia and hyposalivation. The\u00a0aim of this study was to determine the prevalence of these disorders and their risk factors in DM patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>DM patients from two health centers were included. Epidemiological and DM control\u2010related variables were collected. Xerostomia Inventory was filled out by the patients and unstimulated whole salivary flow was collected. Logistic regression tests were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 168 patients were included (46.4% men, 53.6% women, mean age 72.54 [SD 11.03\u2009years]). Thirteen patients had Type 1 DM and 155 had Type 2 DM. 52.4% experienced xerostomia and 41.1% had unstimulated whole salivary flow hyposalivation. Women were more likely to suffer hyposalivation than men (OR 2.5, 95% CI 1.32\u20134.73;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005). Patients with T2DM were less likely to suffer UWS hyposalivation than T1DM patients (OR 0.28, 95% CI 0.08\u20130.95;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04). Glycemic control was not significantly worse in patients with xerostomia and hyposalivation. The drugs for the treatment of DM were not associated with salivary disorders. However, some drugs to treat other comorbidities such hypertension and neurological diseases were associated with xerostomia and hyposalivation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The prevalence of xerostomia and unstimulated whole salivary flow hyposalivation in patients with DM is high. Female sex, T1DM, and the use of certain non\u2010antidiabetic drugs increased the risk of suffering these disorders. The possible association between DM, xerostomia, and\/or hyposalivation is complex and may be influenced by multiple factors. Therefore, further studies are needed to evaluate whether DM influences these salivary disorders.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.13583","type":"journal-article","created":{"date-parts":[[2024,9,29]],"date-time":"2024-09-29T22:03:59Z","timestamp":1727647439000},"page":"622-636","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Xerostomia and Salivary Dysfunction in Patients With Diabetes Mellitus. A Cross\u2010Sectional Study"],"prefix":"10.1111","volume":"53","author":[{"given":"Isabel","family":"S\u00e1nchez Garrido","sequence":"first","affiliation":[{"name":"ORALMED Research Group, Department of Dental Clinical Specialties, Faculty of Odontology Complutense University  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc\u00eda","family":"Ram\u00edrez","sequence":"additional","affiliation":[{"name":"ORALMED Research Group, Department of Dental Clinical Specialties, Faculty of Odontology Complutense University  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Mu\u00f1oz Corcuera","sequence":"additional","affiliation":[{"name":"Department of Clinical Dentistry, School of Biomedical Science European University of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estela","family":"Garrido","sequence":"additional","affiliation":[{"name":"Canal de Panama Health\u2010Care 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