{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:52:19Z","timestamp":1772160739276,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:00:00Z","timestamp":1742342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The diagnosis of oral squamous cell carcinoma (OSqCC) is sometimes delayed. In this study, we attempted to comprehensively analyze the surface and cross section of OSqCC using whole\u2010mount sections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Representative cross sections of 41 pT2 and pT3 OSqCC were digitally assembled, and whole\u2010mount sections were reconstructed. In the cross section of the tumor, the degree of differentiation was classified as well\/moderately differentiated (WDMD) and poorly differentiated (PD); and the surface of the specimen was divided into four types: benign\u2010looking epithelium, dysplasia, carcinoma, and ulceration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the cross\u2010sectional analysis, 17 cases (41.5%) consisted of only WDMD, and the PD component was predominant in seven cases (17.1%). In the remaining 17 patients, the PD component was partial (&lt;\u200950%). When grouping noncancerous lesions (benign\u2010looking epithelium and dysplasia, BnDy) and cancerous lesions (carcinoma and ulceration, CaUl) in the surface analysis, the proportion of CaUl was significantly lower in the tongue than in other oral sites (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.009) In the survival analysis, although not statistically significant, the overall survival of partial PD patients was more similar to that of the predominant PD group compared to that of the WDMD\u2010only group.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.13630","type":"journal-article","created":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T19:09:32Z","timestamp":1742411372000},"page":"343-350","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Histological and Clinical Characteristics of Oral Squamous Cell Carcinoma Analyzed by Digitally Assembled Whole\u2010Mount Sections"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9228-2364","authenticated-orcid":false,"given":"Han Gyeol","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Pathology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"},{"name":"Department of Pathology, Kyung Hee University Hospital Kyung Hee University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nayeon","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manki","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han\u2010Sin","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6089-9340","authenticated-orcid":false,"given":"Junhun","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Pathology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,3,19]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_12_3_1","unstructured":"Board WCoTE \u201cHead and Neck Tumours \u201dBeta Version Ahead of Print International Agency for Research on Cancer Lyon (France). (2022)."},{"key":"e_1_2_12_4_1","unstructured":"National Cancer Institute \u201cSurveillance Epidemiology and End Results Program \u201d https:\/\/seer.cancer.gov."},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-5-291"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/147323001003800302"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.17399"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-013-1412-6"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-019-0444-0"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2020.105014"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2022.05.010"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000149687.90710.21"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.14038"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.14123"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.31.7883"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24589"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2020.104875"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40902-017-0139-8"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2020.105010"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2023.106485"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2023.106466"}],"container-title":["Journal of Oral Pathology &amp; Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jop.13630","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T18:17:59Z","timestamp":1747246679000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jop.13630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,19]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1111\/jop.13630"],"URL":"https:\/\/doi.org\/10.1111\/jop.13630","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/JOP.13630\/v1\/decision1","asserted-by":"object"}]},"ISSN":["0904-2512","1600-0714"],"issn-type":[{"value":"0904-2512","type":"print"},{"value":"1600-0714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,19]]},"assertion":[{"value":"2024-06-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}