{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:52:17Z","timestamp":1772160737939,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T00:00:00Z","timestamp":1745539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["403257\/2012\u20103"],"award-info":[{"award-number":["403257\/2012\u20103"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["475979\/2013\u20103"],"award-info":[{"award-number":["475979\/2013\u20103"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004263","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Rio Grande do Sul","doi-asserted-by":"publisher","award":["16.0471\u20104"],"award-info":[{"award-number":["16.0471\u20104"]}],"id":[{"id":"10.13039\/501100004263","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004263","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Rio Grande do Sul","doi-asserted-by":"publisher","award":["07\/2022"],"award-info":[{"award-number":["07\/2022"]}],"id":[{"id":"10.13039\/501100004263","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Population\u2010based studies on the prevalence of oral mucosal alterations and sociodemographic and behavioral predictors are scarce. The aim of this study was to assess the prevalence of oral mucosal alterations and associated factors in 31\u2010year\u2010old individuals from a Brazilian birth cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Adults from the oral health substudy were included. At the age of 31, information was collected on oral mucosal alterations, including clinical diagnosis, site, size, and self\u2010reported onset time through a clinical examination. After descriptive analyses, associations between independent variables and the presence of potentially malignant oral disorders, developmental alterations, and parulis were tested. Poisson regression models were used to estimate the prevalence ratio of oral mucosal alterations according to sociodemographic, behavioral, and oral health\u2010related variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Oral mucosal alterations had an identified prevalence of 33.5% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009535). The five most prevalent clinical diagnoses were exostosis (18.6%), coated tongue (12.4%), parulis (10.2%), benign oral brownish pigmentation (10.2%), and fissured tongue (9.7%). The tongue was the most common site (29.7%), followed by vestibule or gums (24.3%). In the multivariate analysis, individuals who consumed alcohol frequently had a two\u2010fold increase in oral mucosal alterations prevalence compared to non\u2010users (PR\u2009=\u20092.03; 95% CI\u2009=\u20091.17\u20133.52). Low schooling and tobacco and alcohol consumption were associated with a higher prevalence of oral potentially malignant disorders and parulis (\n                      <jats:italic>p<\/jats:italic>\n                      value \u2264\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There was a high prevalence (33.5%) of oral mucosal alterations, mainly developmental. Prevalence was associated with socioeconomic, behavioral, and oral health\u2010related variables, highlighting the need for comprehensive and multidisciplinary approaches to risk factors to prevent oral diseases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.13638","type":"journal-article","created":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T01:24:53Z","timestamp":1745630693000},"page":"435-444","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Oral Mucosal Alterations: Prevalence and Associated Factors Among 31\u2010Year\u2010Old Adults From a Brazilian Birth Cohort"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1451-7727","authenticated-orcid":false,"given":"Karine Duarte","family":"da Silva","sequence":"first","affiliation":[{"name":"Post\u2010Graduate Program in Dentistry Federal University of Pelotas  Pelotas Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Let\u00edcia Regina Morello","family":"Sartori","sequence":"additional","affiliation":[{"name":"Post\u2010Graduate Program in Dentistry Federal University of Pelotas  Pelotas Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernardo Lessa","family":"Horta","sequence":"additional","affiliation":[{"name":"Post\u2010Graduate Program in Epidemiology Federal University of Pelotas  Pelotas Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fl\u00e1vio Fernando","family":"Demarco","sequence":"additional","affiliation":[{"name":"Post\u2010Graduate Program in Dentistry Federal University of Pelotas  Pelotas Brazil"},{"name":"Post\u2010Graduate Program in Epidemiology Federal University of Pelotas  Pelotas Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos Britto","family":"Correa","sequence":"additional","affiliation":[{"name":"Post\u2010Graduate Program in Dentistry Federal University of Pelotas  Pelotas Brazil"},{"name":"Post\u2010Graduate Program in Epidemiology Federal University of Pelotas  Pelotas Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra Beatriz Chaves","family":"Tarquinio","sequence":"additional","affiliation":[{"name":"Post\u2010Graduate Program in Dentistry Federal University of Pelotas  Pelotas Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/adj.12143"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12264"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.5812\/ircmj.4608"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1980.tb01249.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100528.1991.tb00128.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-83242011000500004"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cdoe.12477"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12308"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12642"},{"key":"e_1_2_9_11_1","first-page":"155","article-title":"Factors Associated With Prevalence of Oral Lesions and Oral Self\u2010Examination in Young Adults From a Birth Cohort in Southern Brazil","volume":"29","author":"Tarquinio S. 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