{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T20:59:01Z","timestamp":1790110741142,"version":"4.0.1"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mucosal melanomas of the head and neck are rare and often diagnosed in the advanced stage. This study examines the incidence, survival and histology of mucosal melanoma compared to its cutaneous counterpart.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This register\u2010based cohort study reviews head and neck melanomas at Helsinki University Hospital, Finland, from 2002 to 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 56 patients with mucosal and 714 with cutaneous melanoma were reviewed. The incidence of head and neck mucosal melanoma in the region was 1.55\/million\/year. The most common sites for mucosal melanomas were the nose and paranasal sinuses. Mucosal melanoma was more common in women, whereas cutaneous melanoma was more common in men (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). A significant difference emerged in mortality between mucosal and cutaneous melanoma, as 5\u2010year survival was only 12.0% in the mucosal melanoma group compared with 60.3% in the cutaneous melanoma group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Mucosal melanoma is a highly aggressive malignancy with poor survival; thus, prompt diagnosis is essential.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.70129","type":"journal-article","created":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T08:17:34Z","timestamp":1771402654000},"page":"676-681","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Mucosal Melanoma of Head and Neck: A Rare and Aggressive Disease\u2014A Register\u2010Based Cohort Study"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-4723-3779","authenticated-orcid":false,"given":"Sara C.","family":"Degerholm","sequence":"first","affiliation":[{"name":"Department of Pathology University of Helsinki and Helsinki University Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuula A.","family":"Salo","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Helsinki and Helsinki University Hospital  Helsinki Finland"},{"name":"Department of Oral and Maxillofacial Diseases, Clinicum, Faculty of Medicine University of Helsinki, Helsinki University Hospital  Helsinki Finland"},{"name":"Translational Immunology Research Program (TRIMM), University of Helsinki  Helsinki Finland"},{"name":"iCAN Digital Precision Cancer Medicine Flagship University of Helsinki  Helsinki Finland"},{"name":"Research Unit of Population Health, Faculty of Medicine University of Oulu  Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti O.","family":"Mauramo","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Helsinki and Helsinki University Hospital  Helsinki 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