{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:16:38Z","timestamp":1788315398172,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Oral cancer is a significant global public health issue, with high morbidity and mortality often linked to late diagnosis. This study evaluated a 12\u2010year oral cancer screening program in northern Portugal to characterize its implementation and outcomes, identifying predictors of lesion detection. The program's outcomes were analyzed to assess its feasibility and contribution to early detection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis of screening program data from 2012 to 2024 was conducted. Participants were recruited through community outreach and selection of high\u2010risk groups in primary care settings. A standardized oral\/oropharyngeal examination protocol was used to classify lesions as benign, suspicious, or malignant based on clinical examination. Demographic data and risk factors were recorded, and individuals with suspicious or malignant lesions were referred for specialized evaluation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 10\u2009433 participants were screened (median age 63\u2009years; 64% female). Oral lesions were detected in 16.7%, with 6.1% classified as suspicious and 0.2% malignant. Current smoking (OR\u2009=\u20091.65;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), former smoking (OR\u2009=\u20091.27;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.010), and previous oncological disease (OR\u2009=\u20091.74;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) were associated with lesion detection on multivariable logistic regression. Overall, 16.4% of participants were referred for specialized consultation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This large\u2010scale screening program successfully reached a broad population, identifying a substantial number of potentially malignant lesions. The association with known risk factors supports the need for targeted screening strategies. Further research should integrate diagnostic confirmation, evaluate long\u2010term patient outcomes, and assess cost\u2010effectiveness to refine oral cancer screening policies and healthcare resource allocation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.70162","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T12:14:22Z","timestamp":1782216862000},"page":"966-975","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictors of Lesion Detection in a 12\u2010Year Oral Cancer Screening Program: A Cohort Study in Northern Portugal"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7112-3580","authenticated-orcid":false,"given":"Miguel","family":"Campos\u2010Lopes","sequence":"first","affiliation":[{"name":"Associa\u00e7\u00e3o Portuguesa de Medicina Dent\u00e1ria Hospitalar\/Unidade M\u00f3vel de Estomatologia e Medicina Dent\u00e1ria  Porto Portugal"},{"name":"Servi\u00e7o de Otorrinolaringologia, Unidade Local de Sa\u00fade de Entre o Douro e Vouga  Santa Maria da Feira Portugal"},{"name":"MEDCIDS\u2014Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine, University of Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Estevinho","sequence":"additional","affiliation":[{"name":"Associa\u00e7\u00e3o Portuguesa de Medicina Dent\u00e1ria Hospitalar\/Unidade M\u00f3vel de Estomatologia e Medicina Dent\u00e1ria  Porto Portugal"},{"name":"Servi\u00e7o de Oncologia M\u00e9dica, Unidade Local de Sa\u00fade de Matosinhos  Matosinhos Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margarida","family":"Gouveia","sequence":"additional","affiliation":[{"name":"Associa\u00e7\u00e3o Portuguesa de Medicina Dent\u00e1ria Hospitalar\/Unidade M\u00f3vel de Estomatologia e Medicina Dent\u00e1ria  Porto Portugal"},{"name":"Unidade de Sa\u00fade Familiar de Aldoar, Unidade Local de Sa\u00fade de Santo Ant\u00f3nio  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo","family":"Subtil","sequence":"additional","affiliation":[{"name":"Associa\u00e7\u00e3o Portuguesa de Medicina Dent\u00e1ria Hospitalar\/Unidade M\u00f3vel de Estomatologia e Medicina Dent\u00e1ria  Porto Portugal"},{"name":"Servi\u00e7o de Medicina Interna, Unidade Local de Sa\u00fade de Tr\u00e1s\u2010Os\u2010Montes e Alto Douro  Vila Real Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Alfaiate","sequence":"additional","affiliation":[{"name":"Associa\u00e7\u00e3o Portuguesa de Medicina Dent\u00e1ria Hospitalar\/Unidade M\u00f3vel de Estomatologia e Medicina Dent\u00e1ria  Porto Portugal"},{"name":"MEDCIDS\u2014Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine, University of Porto  Porto Portugal"},{"name":"Instituto de Ci\u00eancias Biom\u00e9dicas Abel Salazar Universidade Do Porto  Porto Portugal"},{"name":"Faculdade de Ci\u00eancias da Nutri\u00e7\u00e3o e Alimenta\u00e7\u00e3o da Universidade do Porto  Porto Portugal"},{"name":"Departamento de Cirurgia Oral DAVALLMED Clinic  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo","family":"Nogueira","sequence":"additional","affiliation":[{"name":"NOVA National School of Public Health, Public Health Research Center, Comprehensive Health Research Center, CHRC NOVA University Lisbon  Lisbon Portugal"},{"name":"Laborat\u00f3rio Associado TERRA. Instituto de Sa\u00fade Ambiental. Faculdade de Medicina Universidade de Lisboa  Lisboa Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo","family":"Sousa","sequence":"additional","affiliation":[{"name":"NOVA National School of Public Health, Public Health Research Center, Comprehensive Health Research Center, CHRC NOVA University Lisbon  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Leite\u2010Moreira","sequence":"additional","affiliation":[{"name":"Associa\u00e7\u00e3o Portuguesa de Medicina Dent\u00e1ria Hospitalar\/Unidade M\u00f3vel de Estomatologia e Medicina Dent\u00e1ria  Porto Portugal"},{"name":"MEDCIDS\u2014Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine, University of Porto  Porto Portugal"},{"name":"Instituto de Ci\u00eancias Biom\u00e9dicas Abel Salazar Universidade Do Porto  Porto Portugal"},{"name":"Faculdade de Ci\u00eancias da Nutri\u00e7\u00e3o e Alimenta\u00e7\u00e3o da Universidade do Porto  Porto Portugal"},{"name":"Departamento de Cirurgia Oral DAVALLMED Clinic  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,23]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055\u20109965.EPI\u201022\u20100114"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12267"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adaj.2017.07.032"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345211014795"},{"issue":"4","key":"e_1_2_11_6_1","first-page":"303","article-title":"Screening for Oral Cancer","volume":"11","author":"Jitender S.","year":"2016","journal-title":"Journal of Experimental Therapeutics & Oncology"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2020.104632"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14194967"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010173.pub3"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004150.pub4"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.02855"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2022.105936"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.179.4.1790825"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.2018.918"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta10140"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100714.2007.00582.x"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2012.11.004"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(05)66658\u20105"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30517"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102024\u2010086588"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001648\u2010199507000\u201000019"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4808894"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4810069"},{"issue":"1","key":"e_1_2_11_24_1","first-page":"3","article-title":"Evaluation of a Screening Test for the Early Detection of Oral Cancer and Precancer","volume":"12","author":"Jullien J. 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