{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T11:05:13Z","timestamp":1792062313680,"version":"4.4.0"},"reference-count":65,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,9,15]],"date-time":"2015-09-15T00:00:00Z","timestamp":1442275200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Prosthodontics"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The relationship between complete edentulism, which is the terminal outcome of a multifactorial oral disease process and other comorbid diseases, was first reported in 2009. Although the relationship between edentulism and a multitude of systemic diseases was reported, none of the publications studied could determine causality of tooth loss on the incidence of any comorbid disease. Since that publication, there has been a renewed interest in this relationship, and a plethora of new articles have been published. This article will provide an update on articles published since 2008 on the relationship between edentulism and comorbid diseases, and will include the relationship between complete edentulism and such comorbid conditions as malnutrition, obesity, cardiovascular disease, rheumatoid arthritis, pulmonary diseases (including chronic obstructive pulmonary disease), cancer, and even mortality.<\/jats:p>","DOI":"10.1111\/jopr.12350","type":"journal-article","created":{"date-parts":[[2015,9,15]],"date-time":"2015-09-15T11:15:40Z","timestamp":1442315740000},"page":"5-20","source":"Crossref","is-referenced-by-count":119,"title":["Complete Edentulism and Comorbid Diseases: An Update"],"prefix":"10.1111","volume":"25","author":[{"given":"David A.","family":"Felton","sequence":"first","affiliation":[{"name":"Department of Restorative Dentistry West Virginia University School of Dentistry  Morgantown 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