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This study describes a digital workflow to produce an oral positioning radiotherapy stent and analyze its efficacy by measuring dosimetric variations with and without this stent. An oral positioning radiotherapy stent was created according to a digital workflow that included intraoral scanning, digital design, and 3D printing for a patient with squamous cell carcinoma of the tongue. The patient underwent computed tomography to evaluate radiotherapy treatment by intensity\u2010modulated radiation therapy with and without the use of the 3D\u2010printed oral stent. The use of a 3D\u2010printed oral positioning radiotherapy stent is a feasible and reproducible technique that reduced the planning target volume and radiation doses delivered to the hard palate, right parotid gland, and left parotid gland by 42%, 21%, and 8.5%, respectively.<\/jats:p>","DOI":"10.1111\/jopr.13155","type":"journal-article","created":{"date-parts":[[2020,3,4]],"date-time":"2020-03-04T03:05:01Z","timestamp":1583291101000},"page":"448-452","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Digital Workflow for Producing Oral Positioning Radiotherapy Stents for Head and Neck Cancer"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3152-3432","authenticated-orcid":false,"given":"Julia Stephanie","family":"Bruno","sequence":"first","affiliation":[{"name":"Oral Medicine Service Hospital S\u00edrio\u2010Liban\u00eas  Rua Adma Jafet, 91 S\u00e3o Paulo SP 01308\u2010050 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanessa","family":"Miranda\u2010Silva","sequence":"additional","affiliation":[{"name":"Oral Medicine Service Hospital S\u00edrio\u2010Liban\u00eas  Rua Adma Jafet, 91 S\u00e3o Paulo SP 01308\u2010050 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor da Silva","family":"Guedes","sequence":"additional","affiliation":[{"name":"Labsmile Dental Prothesis &amp; 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