{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:38:50Z","timestamp":1785537530280,"version":"3.56.0"},"reference-count":41,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,1,6]],"date-time":"2021-01-06T00:00:00Z","timestamp":1609891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Prosthodontics"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate the fracture resistance and failure modes of endodontically treated mandibular molars restored with different designs of inlays, onlays and endocrowns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Extracted mandibular third molars (n = 180) were used. An access cavity was prepared on the occlusal surface of each tooth and the roots were obturated with gutta percha. All specimens were randomly divided into 6 groups (n = 30\/group) according to the cavity design and the restoration material used. C: control group without access cavity preparation. IE: MOD inlay preparation with EverX Posterior (GC Europe) in the pulp chamber. IG: MOD inlay preparation with G\u2010aenial Universal Flo (GC America) in the pulp chamber. OE: onlay preparation with EverX Posterior (GC Europe) in the pulp chamber. OG: onlay preparation with G\u2010aenial Universal Flo (GC America) in the pulp chamber. EC: endocrown with an empty pulp chamber. All restorations were fabricated with CAD\/CAM system using CERASMART<jats:sup>\u00ae<\/jats:sup> (GC Dental products Europe, Belgium) CAD\/CAM blocks. Specimens were thermal\u2010cycled and were subjected to a compressive load applied at 30\u00b0 angle relative to the long axis of the tooth with a universal testing machine. Results were statistically analyzed by ANOVA followed by Tukey post hoc tests. Chi\u2010square test and Fisher Exact tests were used for the comparisons among groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean fracture strength was significantly different between the groups (<jats:italic>p<\/jats:italic> &lt; 0.001); it was significantly highest for intact teeth, followed by endocrowns (<jats:italic>p<\/jats:italic> = 0.021). The strength was significantly lower for inlays (with G\u2010aenial Universal Flo and EverX Posterior), intermediate for onlays with EverX Posterior followed by onlays with G\u2010aenial Universal Flo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Endocrowns exhibited higher fracture resistance than other tested composite resin groups. Endocrowns and onlays showed a more favorable failure mode than inlay restorations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jopr.13294","type":"journal-article","created":{"date-parts":[[2020,11,21]],"date-time":"2020-11-21T13:53:32Z","timestamp":1605966812000},"page":"625-631","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Effect of Inlays, Onlays and Endocrown Cavity Design Preparation on Fracture Resistance and Fracture Mode of Endodontically Treated Teeth: An In Vitro Study"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5663-6951","authenticated-orcid":false,"given":"Cynthia","family":"Kassis","sequence":"first","affiliation":[{"name":"Department of Esthetic and Restorative Dentistry Saint\u2010Joseph University, School of Dentistry  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3382-4666","authenticated-orcid":false,"given":"Pierre","family":"Khoury","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics Lebanese University, School of Dentistry  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0706-7262","authenticated-orcid":false,"given":"Carina Z","family":"Mehanna","sequence":"additional","affiliation":[{"name":"Department of Esthetic and Restorative Dentistry Saint\u2010Joseph University, School of Dentistry  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6575-3885","authenticated-orcid":false,"given":"Nadim Z.","family":"Baba","sequence":"additional","affiliation":[{"name":"Advanced Education Program in Implant Dentistry Loma Linda University, School of Dentistry  Loma Linda CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fadi","family":"Bou Chebel","sequence":"additional","affiliation":[{"name":"Esthetic and Restorative Dentistry Saint\u2010Joseph University, School of Dentistry  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6882-9227","authenticated-orcid":false,"given":"Maha","family":"Daou","sequence":"additional","affiliation":[{"name":"Dental Materials Saint\u2010Joseph University, School of Dentistry  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Hardan","sequence":"additional","affiliation":[{"name":"Esthetic and Restorative Dentistry Saint\u2010Joseph University, School of Dentistry  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","first-page":"328","DOI":"10.4103\/njcp.njcp_346_18","article-title":"Evaluation of the influence of various restoration techniques on fracture resistance of endodontically treated teeth with different cavity wall thicknesses","volume":"22","author":"Basaran ET","year":"2019","journal-title":"Niger J Clin Pract"},{"key":"e_1_2_6_3_1","first-page":"ZC45","article-title":"The effect of cavity design on fracture resistance and failure pattern in monolithic zirconia partial coverage restorations\u2014an in vitro study","volume":"11","author":"Harsha MS","year":"2017","journal-title":"J Clin Diagn Res"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/1807-3107bor-2018.vol32.0076"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2017.01.022"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7307649"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2019.02.007"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2019.103401"},{"key":"e_1_2_6_9_1","first-page":"392","article-title":"Evidence\u2010based concepts and procedures for bonded inlays and onlays. 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