{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T17:56:45Z","timestamp":1781200605865,"version":"3.54.1"},"reference-count":55,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,9,25]],"date-time":"2022-09-25T00:00:00Z","timestamp":1664064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Prosthodontics"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>This study was conducted to evaluate the clinical peri\u2010implant soft tissue changes during the first year after occlusal loading and the ridge base relation after 3 years for mandibular computer\u2010aided design and computer\u2010aided manufacturing (CAD\u2010CAM) screw\u2010retained implant\u2010supported hybrid prosthesis of polyetheretherketone (PEEK) framework utilized with All\u2010on\u2010Four treatment concept.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Sixteen completely edentulous patients were rehabilitated by four implants following the All\u2010on\u2010Four protocol. After 3 months, the definitive prosthesis was constructed to be a screw\u2010retained CAD\u2010CAM milled framework from the modified PEEK (BioHPP), bonded to polymethylmethacrylate teeth and a pink shaded indirect light\u2010polymerized nanofilled composite resin imitating the soft tissues. Peri\u2010implant soft tissue changes regarding plaque, bleeding, gingival scores, and probing depth were evaluated at prosthesis insertion (T0), 6 months (T1), and 12 months (T2) after insertion. Also, monitoring of the ridge base relation was performed using cone beam computed tomography at time of insertion (T0), and 1 year (T1), 2 years (T2), and 3 years (T3) after mandibular fixed detachable All\u2010on\u2010Four framework insertion. Using Shapiro\u2010Wilk tests using SPSS<jats:sup>\u00ae<\/jats:sup> software version 22 (SPSS Inc., Chicago, IL), all clinical data were nonparametric, while the ridge base relation data were parametric.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were statistically significant differences regarding a plaque, gingival, and bleeding scores for all implants with the advancement of time. However, there was a statistically insignificant difference regarding probing depth in the posterior implants (<jats:italic>p<\/jats:italic> = 0.581). Regarding ridge base relation, there was a significant difference between observation times only in the anterior ridge area in between the two anterior implants (<jats:italic>p<\/jats:italic> = 0.011).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Within the limitations of the study, the full\u2010arch PEEK framework of fixed\u2010detachable, hybrid prosthesis used with the All\u2010on\u2010Four concept for rehabilitation of mandibular edentulous arches is an acceptable treatment approach. Based on the stable ridge base relation posteriorly found in this study, less stress is distributed to the underlining bone due to the shock\u2010absorbing ability of PEEK. Special considerations for frequent soft tissue follow\u2010up and regular maintenance of oral hygiene measures are recommended.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jopr.13602","type":"journal-article","created":{"date-parts":[[2022,9,7]],"date-time":"2022-09-07T07:13:36Z","timestamp":1662534816000},"page":"579-587","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Polyetheretherketone computer\u2010aided design and computer\u2010aided manufacturing framework for All\u2010on\u2010Four mandibular full\u2010arch prosthesis: 3 Years' retrospective study of peri\u2010implant soft tissue changes and ridge base relationship"],"prefix":"10.1111","volume":"32","author":[{"given":"Khloud E.","family":"Mourad","sequence":"first","affiliation":[{"name":"Department of Prosthodontics, Faculty of Dentistry Mansoura University  Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilan Y.","family":"Altonbary","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Faculty of Dentistry Mansoura University  Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radwa M. 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