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This case report shows how virtual planning combined with other digital technologies may improve masticatory function rehabilitation in patients with enlarged mandibular chondrosarcoma. The present study reports a case of a 52\u2010year\u2010old male patient who was initially diagnosed with a mandible chondroma, which was successfully excised with no evidence of malignant transformation. Nevertheless, the patient's symptoms recurred after 10 years, and a subsequent diagnosis of mandible chondrosarcoma was established, prompting the need for subtotal mandible resection and reconstruction with a fibula\u2010free flap. Following a healing period, the patient underwent dental implant surgery to restore the mandibular dental arch, which was performed utilizing computer\u2010aided design and computer\u2010aided manufacturing technology, with fully guided implant placement facilitated by virtual planning. In this case report, the implant position data merging process is described from the digital impression and control model to ensure optimal passive fit of the full\u2010arch zirconia prosthesis and discuss the importance of occlusal adjustments to avoid technical and biological complications. Virtual planning and digital technologies are crucial for the effective management of mandibular defects, allowing for accurate treatment and complete restoration of mandibular function. Their use leads to improved patient outcomes and quality of life. As technology advances, their importance in treating complex medical conditions is only expected to grow.<\/jats:p>","DOI":"10.1111\/jopr.13819","type":"journal-article","created":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T07:00:11Z","timestamp":1703055611000},"page":"409-416","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Virtual planning, guided surgery, and digital prosthodontics in the treatment of extended mandible chondrosarcoma"],"prefix":"10.1111","volume":"33","author":[{"given":"Linas","family":"Zaleckas","sequence":"first","affiliation":[{"name":"Institute of Odontology, Faculty of Medicine Vilnius University  Vilnius Lithuania"},{"name":"Centre of Oral and Maxillofacial Surgery Vilnius University Hospital Zalgiris Clinic Vilnius 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