{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T08:44:05Z","timestamp":1788857045446,"version":"build-2803163510"},"reference-count":53,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T00:00:00Z","timestamp":1715472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002383","name":"King Saud University","doi-asserted-by":"publisher","award":["RSPD2024R790"],"award-info":[{"award-number":["RSPD2024R790"]}],"id":[{"id":"10.13039\/501100002383","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Prosthodontics"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate the fracture resistance of zirconia overlays, considering various preparation designs and the presence of endodontic access.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Ninety translucent zirconia (5Y\u2010PSZ) overlay restorations were divided into six groups (<jats:italic>n<\/jats:italic> = 15\/group) based on different preparation designs, with and without endodontic access: chamfer margin 4\u00a0mm above the gingival level without (group 1) and with endodontic access (group 2); margin 2\u00a0mm above the gingival level without (group 3) and with endodontic access (group 4); overlay with no chamfer margin without (group 5) and with endodontic access (group 6). Restorations were bonded to mandibular first molar resin dies, and the groups with endodontic access were sealed with flowable resin composite. All restorations underwent 100,000 cycles of thermal cycling between 5\u00b0C and 55\u00b0C, followed by loading until fracture. Maximum load and fracture resistance were recorded. ANOVA with Tukey post\u2010hoc tests were used for statistical comparison (<jats:italic>\u03b1<\/jats:italic> &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fracture resistance significantly varied among overlay designs with and without endodontic access (<jats:italic>p<\/jats:italic> &lt; 0.001), except for the no\u2010margin overlays (groups 5 and 6). Overlays with a 2\u00a0mm margin above the gingival margin with endodontic access (group 4) exhibited significantly higher fracture resistance compared to both the 4\u2010mm supragingival (group 2) and no\u2010margin (group 6) designs, even when compared to their respective intact groups (groups 1 and 5). There were no significant differences between the no\u2010margin and 4\u2010mm supragingival overlays.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The more extensive zirconia overlay for mandibular molars is the first choice since the 2\u00a0mm margin above the gingival level design withstood considerable loads even after undergoing endodontic access. A no\u2010margin overlay is preferred over the 4\u2010mm supragingival design as it preserves more tooth structure and there was no outcome difference, irrespective of endodontic access. Caution is warranted in interpreting these findings due to the in vitro nature of the study.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jopr.13865","type":"journal-article","created":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T07:40:05Z","timestamp":1715499605000},"page":"412-421","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Effect of preparation design and endodontic access on fracture resistance of zirconia overlays in mandibular molars: An in vitro study"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7437-4855","authenticated-orcid":false,"given":"Carlos A.","family":"Jurado","sequence":"first","affiliation":[{"name":"Operative Dentistry Division Department of General Dentistry University of Tennessee Health Science Center College of Dentistry  Memphis Tennessee 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