{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:51:37Z","timestamp":1791280297610,"version":"4.1.0"},"reference-count":51,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,8,31]],"date-time":"2024-08-31T00:00:00Z","timestamp":1725062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,8,31]],"date-time":"2024-08-31T00:00:00Z","timestamp":1725062400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Prosthodontics"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Secondary caries around ceramic restorations is the most common reason for the replacement of fixed dental prostheses (FDPs). Therefore, it is important to examine the susceptibility of different ceramic materials to biofilm formation. This study aimed to evaluate biofilm development and associated roughness and color alterations in three lithium disilicate ceramics: Emax CAD (EC), Emax Press (EP), and LiSi Press (LP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Streptococcus mutans<\/jats:italic>\n                      biofilms were grown on the three ceramics (\n                      <jats:italic>n<\/jats:italic>\n                      = 10 per group) for 7 days. Surface roughness values and color alteration were assessed before and after the biofilm using a non\u2010contact profilometer and spectrophotometer, respectively. Biofilm growth was evaluated using colony\u2010forming units (CFUs) and scanning electron microscope (SEM) images. The data were analyzed using one\u2010way ANOVA and Tukey tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was a significant (\n                      <jats:italic>p\u00a0\u2264<\/jats:italic>\n                      \u00a00.001) growth of\n                      <jats:italic>S. mutans<\/jats:italic>\n                      colonies on EC (6.75 \u00b1 0.56) and EP (6.72 \u00b1 0.54) specimens compared to LP, which showed no biofilm growth. The change in average surface roughness (\u2206\n                      <jats:italic>\n                        R\n                        <jats:sub>a<\/jats:sub>\n                      <\/jats:italic>\n                      , nm) was significantly lower (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001) in the EC specimens (0.029 \u00b1 0.003) compared to the EP (0.055 \u00b1 0.012) and LP (0.041 \u00b1 0.010). When the changes in the\n                      <jats:italic>\n                        R\n                        <jats:sub>v<\/jats:sub>\n                      <\/jats:italic>\n                      and\n                      <jats:italic>\n                        R\n                        <jats:sub>t<\/jats:sub>\n                      <\/jats:italic>\n                      values were investigated, no significant difference was observed among the groups. Following the biofilm challenge, the change in color (\u2206\n                      <jats:italic>E<\/jats:italic>\n                      <jats:sub>00<\/jats:sub>\n                      ) was significantly lower (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.005) in the LP group (1.68 \u00b1 1.45) compared to the EC group (3.89 \u00b1 1.50) and no significant difference was observed between the EP group (2.74\u00a0\u00b1\u00a01.01) and the other two ceramics (\n                      <jats:italic>p \u2265<\/jats:italic>\n                      0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      LP ceramics exhibited superior resistance to\n                      <jats:italic>S. mutans<\/jats:italic>\n                      biofilm formation and associated changes in surface roughness and color compared to the Emax CAD and Emax Press ceramics. These findings suggest that the LiSi Press material may be more favorable to mitigate the risk of secondary caries.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jopr.13944","type":"journal-article","created":{"date-parts":[[2024,8,31]],"date-time":"2024-08-31T05:26:55Z","timestamp":1725082015000},"page":"1304-1311","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The impact of\n                    <i>Streptococcus mutans<\/i>\n                    biofilms on the color stability and topographical features of three lithium disilicate ceramics"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6678-7940","authenticated-orcid":false,"given":"Abdulrahman A.","family":"Balhaddad","sequence":"first","affiliation":[{"name":"Department of Restorative Dental Sciences College of Dentistry Imam Abdulrahman Bin Faisal University Dammam Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulkareem Muneer","family":"Al Otaibi","sequence":"additional","affiliation":[{"name":"Department of Substitutive Dental Sciences College of Dentistry Imam Abdulrahman Bin Faisal University Dammam Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalid Saud","family":"Alotaibi","sequence":"additional","affiliation":[{"name":"College of Dentistry Imam Abdulrahman Bin Faisal University Dammam Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0413-8387","authenticated-orcid":false,"given":"Afnan O.","family":"Al\u2010Zain","sequence":"additional","affiliation":[{"name":"Restorative Dentistry Department Faculty of Dentistry King Abdulaziz University Jeddah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1539-798X","authenticated-orcid":false,"given":"Eman H.","family":"Ismail","sequence":"additional","affiliation":[{"name":"Department of Clinical Dental Sciences College of Dentistry Princess Nourah bint Abdulrahman University Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8180-8903","authenticated-orcid":false,"given":"Yousif A.","family":"Al\u2010Dulaijan","sequence":"additional","affiliation":[{"name":"Department of Substitutive Dental Sciences College of Dentistry Imam Abdulrahman Bin Faisal University Dammam Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3288-4720","authenticated-orcid":false,"given":"Haidar","family":"Alalawi","sequence":"additional","affiliation":[{"name":"Department of Substitutive Dental Sciences College of Dentistry Imam Abdulrahman Bin Faisal University Dammam Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7402-9242","authenticated-orcid":false,"given":"Ahmad M.","family":"Al\u2010Thobity","sequence":"additional","affiliation":[{"name":"Department of Substitutive Dental Sciences College of Dentistry Imam Abdulrahman Bin Faisal University Dammam Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19103157"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-019-03641-9"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12361"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2022.104140"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering7030083"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/ma8062887"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2022.08.005"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/nano10102001"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.14105"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jopr.13260"},{"key":"e_1_2_9_12_1","unstructured":"AlmogbelL Sadid\u2010ZadehR \u00d6rgevA et\u00a0al.Flexural strength surface roughness and biofilm formation of ceramic\u2010reinforced PEEK: an in vitro comparative study. 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