{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:47:20Z","timestamp":1785844040521,"version":"3.56.0"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Prosthodontics"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Although peri\u2011implantitis is known to affect adjacent natural teeth, its site\u2011specific influence on neighboring implants remains poorly characterized. The purpose of this retrospective study was to evaluate whether peri\u2011implantitis exerts localized, site\u2011specific detrimental effects on adjacent dental implants and to determine whether these effects differ between mesial and distal adjacent implants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A retrospective chart review was conducted on patients with two or more adjacent implants in function for \u22651 year, in which at least one implant was diagnosed with peri\u2010implantitis. Clinical parameters such as probing depth (PD), relative probing depth (RPD), free mucosal margin (FMM), bleeding on probing (BOP) and radiographic bone levels were recorded and analyzed using linear and generalized linear mixed\u2010effects models, accounting for patient\u2010level clustering.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifty\u2010three patients contributed to 78 peri\u2010implantitis affected main implants and 100 adjacent implants. Overall, RPD was significantly greater at near sites than far sites (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.0237), and FMM was more apical at near sites than far sites (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.007). Distal adjacent implants showed significantly deeper PD (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.037) and greater RPD (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.034) at near sites, whereas mesial adjacent implants exhibited only increased recession (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.012) compared to far sites. Marginal bone loss differences were small and not statistically significant. Notably, 53% of adjacent implants developed peri\u2010implantitis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Peri\u2010implantitis exerts localized, site\u2010specific effects on adjacent implants, with more pronounced soft\u2010tissue breakdown at near surfaces, particularly affecting distal neighbors. These findings underscore the need for close monitoring of implants adjacent to peri\u2010implantitis sites.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jopr.70205","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:31:19Z","timestamp":1785843079000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of peri\u2010implantitis on adjacent dental implants: A retrospective analysis"],"prefix":"10.1111","author":[{"given":"Chris","family":"Gupta","sequence":"first","affiliation":[{"name":"Division of Comprehensive Dentistry School of Dentistry Louisiana State University Health Sciences Center  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinayak","family":"Joshi","sequence":"additional","affiliation":[{"name":"Department of Periodontics School of Dentistry Louisiana State University Health Sciences Center  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8279-3766","authenticated-orcid":false,"given":"Vivek","family":"Thumbigere\u2010Math","sequence":"additional","affiliation":[{"name":"Division of Periodontology University of Maryland School of Dentistry  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne","family":"St Germain","sequence":"additional","affiliation":[{"name":"Department of Periodontics School of Dentistry Louisiana State University Health Sciences Center  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amjila","family":"Bam","sequence":"additional","affiliation":[{"name":"Biostatistics and Data Science School of Public Health Louisiana State University Health Sciences Center  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingzhao","family":"Yu","sequence":"additional","affiliation":[{"name":"Biostatistics and Data Science School of Public Health Louisiana State University Health Sciences Center  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6661-7930","authenticated-orcid":false,"given":"Eswar","family":"Kandaswamy","sequence":"additional","affiliation":[{"name":"Department of Periodontics School of Dentistry Louisiana State University Health Sciences Center  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,4]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12994"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2014.10.023"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034511431252"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12954"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.10758"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2017.04.011"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.25\u20100270"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004970.pub5"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967\u2010022\u201003636\u20109"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/ID.0b013e3181effa53"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/dj12080251"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1466417"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.20\u20100124"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.14316"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.14147"},{"key":"e_1_2_9_17_1","unstructured":"STROBE\u2014Strengthening the reporting of observational studies in epidemiology [Internet]. 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Available from:https:\/\/www.strobe\u2010statement.org\/"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.10415"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12791"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2018.01.004"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8020279"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.9271"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtemb.2024.127464"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12372"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12150"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11206188"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40729\u2010019\u20100180\u20108"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11164812"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.5037\/jomr.2016.7302"},{"key":"e_1_2_9_30_1","volume-title":"Proper Oral Hygiene Measures to Maintain Healthy Soft Tissues Around Dental Implants","author":"Kim I","year":"2024"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/biostatistics\/kxn010"}],"container-title":["Journal of Prosthodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jopr.70205","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jopr.70205","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jopr.70205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:31:26Z","timestamp":1785843086000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jopr.70205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,4]]},"references-count":30,"alternative-id":["10.1111\/jopr.70205"],"URL":"https:\/\/doi.org\/10.1111\/jopr.70205","archive":["Portico"],"relation":{},"ISSN":["1059-941X","1532-849X"],"issn-type":[{"value":"1059-941X","type":"print"},{"value":"1532-849X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,4]]},"assertion":[{"value":"2026-02-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"jopr.70205"}}