{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T05:29:06Z","timestamp":1787117346061,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:00:00Z","timestamp":1787011200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:00:00Z","timestamp":1787011200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100008528","name":"Academy of Osseointegration","doi-asserted-by":"publisher","award":["283204"],"award-info":[{"award-number":["283204"]}],"id":[{"id":"10.13039\/100008528","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Prosthodontics"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To longitudinally assess the frequency and magnitude of interproximal contact loss (ICL) between implant crowns and adjacent teeth, and changes in tactile sensitivity thresholds around single implant restorations compared with contralateral natural teeth over 18 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A prospective cohort study was conducted on 20 participants who were restored with a single posterior implant crown. Each restoration used a custom\u2010milled titanium abutment and a screw\u2010retained monolithic zirconia crown. Occlusion was standardized to light centric contacts on the implant crowns, and follow\u2010ups were conducted at 1, 3, 6, 12, and 18 months. Interproximal contact tightness was quantified with a digital force gauge using 0.22\u2010mm floss and open contact was measured at 0\u00a0N. Frictional forces were analyzed with repeated\u2010measures and between\u2010subjects ANOVA. Tactile sensibility was tested with foils with a thickness of 8\u2013100\u00a0\u00b5m at implant and control sites, and detection of tactile sensitivity was modeled by logistic regression to estimate 50% detection thresholds. Peri\u2010implant indices, modified Plaque Index, probing depth, and bleeding on probing were recorded to assess the health of the peri\u2010implant soft tissue.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      All contacts were closed at baseline; ICL occurred in two implant crowns (10%), confined to the mandible, and did not progress after 6 months. Interproximal frictional forces showed a nonsignificant time trend (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.06) with no mesial\u2013distal or tooth\u2010group differences. For tactile sensitivity, controls outperformed implants at 24\u00a0\u00b5m (\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.02) at 3 months; by 18 months, group differences were nonsignificant. Detection thresholds improved from \u223c39\u201340\u00a0\u00b5m at 3 months to \u223c20\u00a0\u00b5m at 18 months (\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.045). At \u226580\u00a0\u00b5m, all participants detected contacts at all sites and timepoints. Peri\u2010implant health remained stable; no implants demonstrated clinical signs consistent with peri\u2010implantitis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Within the 18\u2010month observation period, single posterior implant restorations under controlled occlusion demonstrated early adaptive proximal contact stability and functional tactile adaptation. Most contact changes occurred within the first 6 months, primarily in mandibular sites, emphasizing the importance of early monitoring. Peri\u2010implant clinical parameters remained stable during follow\u2010up. Clinically, maintaining occlusal contacts and regular follow\u2010up can support proximal stability during the early phase of function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jopr.70208","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T05:17:49Z","timestamp":1787116669000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Early changes in interproximal contact and tactile sensitivity around implant\u2010supported restorations: An 18\u2010month prospective study"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4362-4251","authenticated-orcid":false,"given":"Diana","family":"Lopez","sequence":"first","affiliation":[{"name":"Department of Restorative Dentistry and Biomaterials Sciences Harvard School of Dental Medicine  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9321-7960","authenticated-orcid":false,"given":"Huilin","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry and Biomaterials Sciences Harvard School of Dental Medicine  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6077-1198","authenticated-orcid":false,"given":"Suhwan","family":"Bong","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason D.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry and Biomaterials Sciences Harvard School of Dental Medicine  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2631-7722","authenticated-orcid":false,"given":"Jae\u2010Hyun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry and Biomaterials Sciences Harvard School of Dental Medicine  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7142-2890","authenticated-orcid":false,"given":"Sang J.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry and Biomaterials Sciences Harvard School of Dental Medicine  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2020.12.043"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2012.02547.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jopr.12552"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301\u20100503(81)80007\u20100"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13152"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12373"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2015.08.018"},{"issue":"6","key":"e_1_2_8_9_1","first-page":"535","article-title":"Statistical analysis of the diachronic loss of interproximal contact between fixed implant prostheses and adjacent teeth","volume":"23","author":"Koori 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