{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T07:27:32Z","timestamp":1787038052840,"version":"build-2736575974"},"reference-count":20,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:00:00Z","timestamp":1787011200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:00:00Z","timestamp":1787011200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Prosthodontics"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To compare long\u2010term outcomes, complications, patient\u2010reported outcomes, and costs of tooth preservation (endodontic treatment followed by long\u2010term prosthodontic restoration) versus extraction with implant replacement at the endodontic\u2013prosthodontic interface.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A retrospective dual\u2010center private\u2010practice cohort of adults treated with a SAVE pathway or an IMPLANT pathway was evaluated over a 10\u2010year study period with follow\u2010up from 1.0 to 9.6 years after the index unit entered function. Time\u2010to\u2010failure, complications, patient\u2010reported outcomes, and costs were analyzed using Kaplan\u2013Meier\/log\u2010rank methods and Cox proportional hazards regression. A propensity\u2010score inverse probability of treatment weighting (IPTW) sensitivity analysis was performed to address confounding by indication and the numerical imbalance between treatment pathways.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The adjusted analytic cohort comprised 859 cases with complete baseline covariates (594 SAVE; 265 IMPLANT); 860 cases were eligible for survival follow\u2010up. Median follow\u2010up was 3.1 years interquartile range (IQR 1.8\u20134.7; range 1.0\u20139.6). Failure occurred in 51 cases (37 SAVE; 14 IMPLANT). Estimated survival at 1 year was 97.8% for SAVE and 98.5% for IMPLANT, and estimated survival at the end of the observed follow\u2010up window was 93.8% and 94.7%, respectively. There was no evidence of a survival difference between pathways (log\u2010rank\n                      <jats:italic>p<\/jats:italic>\n                      = 0.785). Implant replacement was not associated with a lower adjusted hazard of failure (hazard ratio [HR] 0.87; 95% confidence interval (CI) 0.47\u20131.62;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.666), whereas current tobacco use increased failure risk (HR 2.01; 95% CI 1.05\u20133.86;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.036). Patient\u2010reported oral health\u2013related quality of life (OHRQoL) and satisfaction were comparable. IMPLANT involved more visits, greater downtime, and higher initial, total observed, and cost\u2010per\u2010year\u2010of\u2010function expenses (all\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this private\u2010practice cohort, appropriately indicated tooth preservation and implant replacement demonstrated comparable survival and patient\u2010reported outcomes within the observed follow\u2010up period. The two options should not be treated as interchangeable substitutes; rather, selection should be individualized according to restorability, ferrule feasibility, periodontal and occlusal risk, strategic value, patient preference, maintenance burden, and cost trajectory.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jopr.70222","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T07:04:02Z","timestamp":1787036642000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Save or extract: A 10\u2010year dual\u2010center cohort comparing tooth preservation with implant replacement"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-1010-7065","authenticated-orcid":false,"given":"Sagar J.","family":"Abichandani","sequence":"first","affiliation":[{"name":"Department of Prosthodontics The Dental Hub (Silverline Dent and Care Solutions Pvt. Ltd.)  Mumbai Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5854-7917","authenticated-orcid":false,"given":"Aneendita","family":"Dutta","sequence":"additional","affiliation":[{"name":"Researcher The Dental Hub (Silverline Dent and Care Solutions Pvt. Ltd.)  Mumbai Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034513512371"},{"key":"e_1_2_8_3_1","first-page":"96","article-title":"For teeth requiring endodontic treatment, what are the differences in outcome of restored endodontically treated teeth compared with implant\u2010supported restorations?","volume":"22","author":"Iqbal MK","year":"2007","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2011.03.026"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100528.1997.tb00941.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17\u20100739"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.070210"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1991.62.1.51"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1996.67.7.666"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022\u20103913(10)60096\u20100"},{"issue":"4","key":"e_1_2_8_11_1","first-page":"366","article-title":"Treatment planning: teeth versus implants","volume":"16","author":"Lewis S","year":"1996","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2006.0318"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022\u20103913(07)60102\u20104"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708\u20108208.2012.00456.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2019.03.008"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2017.06.005"},{"issue":"12","key":"e_1_2_8_17_1","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1111\/j.1365-2591.2007.01322.x","article-title":"Outcome of primary root canal treatment: systematic review of the literature\u2010part 1. 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