{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T10:54:55Z","timestamp":1791284095850,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Prosthodontics"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the influence of different cariostatic agents: 38% silver diamine fluoride (SDF), 38% SDF\u00a0+\u00a0potassium iodide (RS), and nano silver fluoride (NSF) compared with distilled water (control), on the surface roughness and color change of CAD\u2013CAM\u2010milled restorative materials: nanoceramic resin (NR), feldspathic ceramic (FC), and lithium disilicate ceramic (LD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      Thirty\u2010two specimens of each material were fabricated and allocated into four experimental groups (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a08). The specimens underwent repeated applications of the cariostatic agents (3\u00a0min, repeated six times) and were evaluated for surface roughness (\u2206Ra) by profilometry and for color change using a digital spectrophotometer, with analysis based on the CIEDE2000 system (\u2206\n                      <jats:italic>E<\/jats:italic>\n                      <jats:sub>00<\/jats:sub>\n                      ). Data were analyzed using two\u2010way analysis of variance (ANOVA), followed by one\u2010way ANOVA or Kruskal\u2013Wallis tests with appropriate post hoc comparisons and Bonferroni correction (\n                      <jats:italic>\u03b1<\/jats:italic>\n                      \u00a0=\u00a00.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A statistically significant interaction was observed between restorative material type and the applied cariostatic agent. SDF produced the greatest increases in roughness, especially in LD (\u2206Ra\u00a0=\u00a00.232) and FC (\u2206Ra\u00a0=\u00a00.126), compared with the control group (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001), and color\u2010change values far above clinically acceptable thresholds (\u2206\n                      <jats:italic>E<\/jats:italic>\n                      <jats:sub>00<\/jats:sub>\n                      \u00a0=\u00a030.56\u201345.72;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). Potassium iodide application after SDF (RS) showed low color change across all restorative materials (\u2206\n                      <jats:italic>E<\/jats:italic>\n                      <jats:sub>00<\/jats:sub>\n                      \u00a0=\u00a00.28\u20130.75) and increased roughness in the FC. NSF showed behavior similar to the control group in terms of roughness and maintained color\u2010change values within acceptable limits (\u2206\n                      <jats:italic>E<\/jats:italic>\n                      <jats:sub>00<\/jats:sub>\n                      \u00a0=\u00a00.57\u20131.35).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>SDF may compromise the surface roughness and color change of CAD\u2013CAM\u2010milled restorative materials, whereas NSF and RS show potential as more favorable alternatives for the evaluated outcomes.<\/jats:p>\n                  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