{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:50:52Z","timestamp":1791352252903,"version":"4.3.1"},"reference-count":50,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Prosthodontics"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To investigate the amount of bone\u2010height change in the posterior edentulous mandible restored with full\u2010arch implant\u2010supported fixed complete dentures (FCDs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A search was conducted in the Ovid MEDLINE, Embase, Web of Science, and EBSCOhost Dentistry and Oral Sciences databases for clinical studies on bone\u2010height change in the posterior edentulous mandible restored with FCDs. The full\u2010text articles were selected based on inclusion and exclusion criteria by two reviewers. Risk of bias assessment of the included studies was conducted using the methodological index for non\u2010randomized studies (MINORS). Meta\u2010analysis was performed using a random\u2010effects model to estimate bone height change in the posterior mandible with a 95% confidence interval (CI). The statistical significance was defined as\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value (&lt;0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 7,224 publications were identified through electronic databases and manual search. Twelve cohort studies were selected for qualitative assessment and eight for quantitative analysis. The pooled bone\u2010height change was 0.67\u00a0mm (95% CI: 0.29\u20131.05\u00a0mm);\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.001) with high heterogeneity based on chi\u2010square and\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      statistics (\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u00a0=\u00a097.63%;\n                      <jats:italic>\u03c4<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u00a0=\u00a00.43). Subgroup analysis based on implant type as covariate demonstrated that endosseous implants were associated\u00a0with statistically significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) increase in bone height of the posterior edentulous mandible, but not transosseous implants, although the between\u2010subgroup difference was not significant (\n                      <jats:italic>Q<\/jats:italic>\n                      \u00a0=\u00a00.284;\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.594). MINORS scores were 10\u201313 of 16 for one\u2010arm studies and 20 of 24 for the single two\u2010arm study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Within the limitations of this review and meta\u2010analysis, FCDs were associated with a statistically significant increase in posterior mandibular bone height, although high heterogeneity and a prediction interval spanning bone loss limit the generalizability of this finding. Further standardized prospective studies are needed to clarify the factors underlying this variability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jopr.70253","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:17:42Z","timestamp":1791350262000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Posterior edentulous mandibular bone\u2010height change with implant\u2010supported fixed complete dentures: A systematic review and meta\u2010analysis"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-9377-558X","authenticated-orcid":false,"given":"Sieu Yien","family":"Chiam","sequence":"first","affiliation":[{"name":"Clinical Assistant Professor Section of Prosthodontics, School of Dentistry University of California Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han\u2010Pang","family":"Liu","sequence":"additional","affiliation":[{"name":"Private Practice Arts Dental Clinic  Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2868-9490","authenticated-orcid":false,"given":"Won\u2010Suk","family":"Oh","sequence":"additional","affiliation":[{"name":"Clinical Professor Department of Biologic and Materials Sciences &amp; Prosthodontics University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1067\/mpr.2001.117609","article-title":"Some clinical factors related to rate of resorption of residual ridges. 1962","volume":"86","author":"Atwood DA","year":"2001","journal-title":"J Prosthet Dent"},{"key":"e_1_2_8_3_1","article-title":"The continuing reduction of the residual alveolar ridges in complete denture wearers: a mixed\u2010longitudinal study covering 25 years","author":"Tallgren A","journal-title":"J Prosthet Dent"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3109\/00016358809004759","article-title":"Mandibular bone resorption in patients treated with tissue\u2010integrated prostheses and in complete\u2010denture wearers","volume":"46","author":"Sennerby L","year":"1988","journal-title":"Acta Odontol Scand"},{"key":"e_1_2_8_5_1","doi-asserted-by":"crossref","first-page":"53","DOI":"10.4047\/jap.2014.6.1.53","article-title":"Residual bone height measured by panoramic radiography in older edentulous Korean patients","volume":"6","author":"Liang XH","year":"2014","journal-title":"J Adv Prosthodont"},{"key":"e_1_2_8_6_1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/ID.0000000000000489","article-title":"Ridge dimensions of the edentulous mandible in posterior sextants: an observational study on cone beam computed tomography radiographs","volume":"26","author":"Bressan E","year":"2017","journal-title":"Implant Dent"},{"key":"e_1_2_8_7_1","first-page":"15","article-title":"Electrical phenomena in biorheology","volume":"19","author":"Fukada E","year":"1982","journal-title":"Biorheology"},{"issue":"1","key":"e_1_2_8_8_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s002239900384","article-title":"Perspectives: some roles of mechanical usage, muscle strength and the mechanostat in skeletal physiology, disease and research","volume":"62","author":"Frost HM","year":"1998","journal-title":"Calcif Tissue Int"},{"key":"e_1_2_8_9_1","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.joms.2004.07.023","article-title":"Tensile mechanical strain up\u2010regulates Runx2 and osteogenic factor expression in human periosteal cells: implications for distraction osteogenesis","volume":"63","author":"Kanno T","year":"2005","journal-title":"J Oral Maxillofac Surg"},{"key":"e_1_2_8_10_1","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.5272\/jimab.2017231.1432","article-title":"Mandibular flexure\u2014A reason for chronic pain syndrome in edentulous patient restored with fixed ZrO2 construction over implants, inserted in natural bone and bone graft area. Case report","volume":"23","author":"Abadzhiev M","year":"2017","journal-title":"J IMAB"},{"key":"e_1_2_8_11_1","first-page":"18","article-title":"Bone induction and bone loss by use of the TMI","volume":"2","author":"Bosker H","year":"1991","journal-title":"Oral Surg Diagn"},{"key":"e_1_2_8_12_1","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0278-2391(95)90230-9","article-title":"Reconstruction of the severely atrophic edentulous mandible with the transmandibular implant system","volume":"53","author":"Betts NJ","year":"1995","journal-title":"J Oral Maxillofac Surg"},{"key":"e_1_2_8_13_1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1177\/10454411000110010101","article-title":"Biomechanics of the mandible","volume":"11","author":"Van Eijden TM","year":"2000","journal-title":"Crit Rev Oral Biol Med"},{"key":"e_1_2_8_14_1","first-page":"115","article-title":"A finite element stress analysis of the transmandibular implant system","volume":"14","author":"Williams KR","year":"2001","journal-title":"Int J Prosthodont"},{"key":"e_1_2_8_15_1","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1002\/jbm.b.30606","article-title":"Finite element analysis of a transmandibular implant","volume":"80","author":"Nomura T","year":"2007","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"e_1_2_8_16_1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1741-2358.2004.00005.x","article-title":"Responses of jawbone to pressure","volume":"21","author":"Carlsson GE","year":"2004","journal-title":"Gerodontology"},{"key":"e_1_2_8_17_1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0142-9612(83)90065-0","article-title":"Osseointegrated titanium fixtures in the treatment of edentulousness","volume":"4","author":"Br\u00e5nemark PI","year":"1983","journal-title":"Biomaterials"},{"key":"e_1_2_8_18_1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1563\/1548-1336(1998)024<0093:EOINOT>2.3.CO;2","article-title":"Effect of implant number on transverse bending moments during simulated unilateral loading of mandibular fixed\u2010detachable prostheses","volume":"24","author":"Korioth TW","year":"1998","journal-title":"J Oral Implantol"},{"key":"e_1_2_8_19_1","first-page":"602","article-title":"Implant treatment in the edentulous mandible: a prospective study on Br\u00e5nemark system implants over more than 20 years","volume":"16","author":"Ekelund JA","year":"2003","journal-title":"Int J Prosthodont"},{"key":"e_1_2_8_20_1","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1016\/j.jdent.2014.05.016","article-title":"Systematic review of short\u2010 (5\u201010 years) and long\u2010term (10 year or more) survival and success of full\u2010arch fixed dental hybrid prostheses and supporting implants","volume":"42","author":"Kwon T","year":"2014","journal-title":"J Dent"},{"key":"e_1_2_8_21_1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1615\/JLongTermEffMedImplants.2019030866","article-title":"The effect of mandibular flexure on stress distribution in the all\u2010on\u20104 treated edentulous mandible: a comparative finite\u2010element study based on mechanostat theory","volume":"29","author":"Shahriari S","year":"2019","journal-title":"J Long Term Eff Med Implants"},{"key":"e_1_2_8_22_1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.11607\/jomi.7744","article-title":"Effects of cantilever length and implant inclination on the stress distribution of mandibular prosthetic restorations constructed from monolithic zirconia ceramic","volume":"35","author":"Durkan R","year":"2020","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_8_23_1","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1111\/jopr.12519","article-title":"Ratios of cantilever lengths and anterior\u2010posterior spreads of definitive hybrid full\u2010arch, screw\u2010retained prostheses: results of a clinical study","volume":"27","author":"Drago C","year":"2018","journal-title":"J Prosthodont"},{"key":"e_1_2_8_24_1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/jopr.13012","article-title":"A 30\u2010year follow\u2010up of a patient with mandibular complete\u2010arch fixed implant\u2010supported prosthesis on 4 implants: a clinical report","volume":"28","author":"Balshi TJ","year":"2019","journal-title":"J Prosthodont"},{"key":"e_1_2_8_25_1","first-page":"151","article-title":"Changes in masticatory function in complete denture wearers after insertion of bridges on osseointegrated implants in the lower jaw","volume":"4","author":"Lindquist LW","year":"1982","journal-title":"Adv Biomater"},{"key":"e_1_2_8_26_1","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1080\/10255842.2013.792916","article-title":"Influence of mastication and edentulism on mandibular bone density","volume":"18","author":"Chou HY","year":"2015","journal-title":"Comput Methods Biomech Biomed Engin"},{"key":"e_1_2_8_27_1","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1177\/00220345940730101001","article-title":"Within\u2010subject comparisons of implant\u2010supported mandibular prostheses: evaluation of masticatory function","volume":"73","author":"Feine JS","year":"1994","journal-title":"J Dent Res"},{"key":"e_1_2_8_28_1","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/0022-3913(83)90361-X","article-title":"Biomechanical considerations in osseointegrated prostheses","volume":"49","author":"Skalak R","year":"1983","journal-title":"J Prosthet Dent"},{"key":"e_1_2_8_29_1","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S0278-2391(89)80005-9","article-title":"The transmandibular implant: a 2\u2010year prospective study","volume":"47","author":"Powers MP","year":"1989","journal-title":"J Oral Maxillofac Surg"},{"key":"e_1_2_8_30_1","first-page":"227","article-title":"Osteogenesis of the mandible associated with implant reconstruction: a patient report","volume":"4","author":"Taylor TD","year":"1989","journal-title":"Int I Oral Maxillofac Implants"},{"key":"e_1_2_8_31_1","first-page":"541","article-title":"Reparative bone growth in an extremely atrophied edentulous mandible stimulated by an osseointegrated implant\u2010support fixed prosthesis: a case report","volume":"7","author":"Oikarinen VJ","year":"1992","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_8_32_1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00008505-199304000-00004","article-title":"Osseous changes following placement of the transmandibular implant system in edentulous mandibles","volume":"2","author":"Betts NJ","year":"1993","journal-title":"Implant Dent"},{"key":"e_1_2_8_33_1","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1563\/0-721.1","article-title":"A 24\u2010year retrospective study of bone growth after implant placement","volume":"31","author":"Roberts RA","year":"2005","journal-title":"J Oral Implantol"},{"key":"e_1_2_8_34_1","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/S0278-2391(10)80064-3","article-title":"The transmandibular implant: from progressive bone loss to controlled bone growth","volume":"52","author":"Powers MP","year":"1994","journal-title":"J Oral Maxillofac Surg"},{"key":"e_1_2_8_35_1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0278-2391(97)90436-5","article-title":"Bone level changes in patients with transmandibular implants","volume":"55","author":"Kwakman JM","year":"1997","journal-title":"J Oral Maxillofac Surg"},{"key":"e_1_2_8_36_1","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.14219\/jada.archive.1999.0372","article-title":"Using restorations borne totally by anterior implants to preserve the edentulous mandible","volume":"130","author":"Davis WH","year":"1999","journal-title":"J Am Dent Assoc"},{"key":"e_1_2_8_37_1","first-page":"419","article-title":"Osseous proliferation of the mandible after placement of endosseous implants","volume":"15","author":"Nakai H","year":"2000","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_8_38_1","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1046\/j.1365-2842.2001.00712.x","article-title":"The use of the transmandibular implant system in extreme atrophy of the mandible; a retrospective study of the results in two different hospital situations","volume":"28","author":"Verhoeven JW","year":"2001","journal-title":"J Oral Rehabil"},{"key":"e_1_2_8_39_1","first-page":"315","article-title":"Mandibular growth following implant restoration: does Wolff's law apply to residual ridge resorption?","volume":"22","author":"Reddy MS","year":"2002","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_8_40_1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1034\/j.1600-0501.2002.130207.x","article-title":"The effects of fixed and removable implant\u2010stabilised prostheses on posterior mandibular residual ridge resorption","volume":"13","author":"Wright PS","year":"2002","journal-title":"Clin Oral Implants Res"},{"key":"e_1_2_8_41_1","doi-asserted-by":"crossref","first-page":"854","DOI":"10.11607\/jomi.2768","article-title":"A retrospective analysis of mandibular bone height changes associated with 81 screw\u2010retained implant\u2010supported prostheses with distal cantilevers: a long\u2010term follow\u2010up analysis","volume":"28","author":"Dhima M","year":"2013","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_8_42_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta\u2010analysis protocols (PRISMA\u2010P) 2015 statement","volume":"4","author":"Moher D","year":"2015","journal-title":"Syst Rev"},{"key":"e_1_2_8_43_1","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1046\/j.1445-2197.2003.02748.x","article-title":"Methodological index for non\u2010randomized studies (MINORS): development and validation of a new instrument","volume":"73","author":"Slim K","year":"2003","journal-title":"ANZ J Surg"},{"key":"e_1_2_8_44_1","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta\u2010analyses","volume":"327","author":"Higgins JP","year":"2003","journal-title":"BMJ"},{"key":"e_1_2_8_45_1","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/s13643-021-01626-4","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"10","author":"Page MJ","year":"2021","journal-title":"Syst Rev"},{"key":"e_1_2_8_46_1","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1563\/aaid-joi-D-20-00010","article-title":"Can implant\u2010retained fixed prostheses trigger bone response in the posterior region of edentulous mandibles? A 32\u2010month cone\u2010beam computerized tomography study analyzing bone height and density","volume":"47","author":"Font\u00e3o FNGK","year":"2021","journal-title":"J Oral Implantol"},{"key":"e_1_2_8_47_1","doi-asserted-by":"crossref","first-page":"199","DOI":"10.11607\/jomi.9077","article-title":"Long\u2010term results of intraforaminal immediately loaded implants and posterior mandibular regrowth evaluation in severely atrophic mandibles","volume":"37","author":"Testori T","year":"2022","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_8_48_1","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1002\/ar.a.10119","article-title":"Bone's mechanostat: a 2003 update","volume":"275","author":"Frost HM","year":"2003","journal-title":"Anat Rec A Discov Mol Cell Evol Biol"},{"issue":"16","key":"e_1_2_8_49_1","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12165302","article-title":"Biomechanical implications of mandibular flexion on implant\u2010supported full\u2010arch rehabilitations: a systematic literature review","volume":"12","author":"Caggiano M","year":"2023","journal-title":"J Clin Med"},{"issue":"11","key":"e_1_2_8_50_1","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1111\/clr.14327","article-title":"Factors affecting radiographic marginal bone resorption at dental implants in function for at least 5 years: a multicenter retrospective study","volume":"35","author":"Trombelli L","year":"2024","journal-title":"Clin Oral Implants Res"},{"key":"e_1_2_8_51_1","doi-asserted-by":"crossref","DOI":"10.3389\/fdmed.2024.1465137","article-title":"Implant\u2010supported prosthesis under progressive loading protocol stimulates alveolar bone growth in patients with severe alveolar bone atrophy. Retrospective case series","volume":"5","author":"Anitua E","year":"2024","journal-title":"Front Dent Med"}],"container-title":["Journal of Prosthodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jopr.70253","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jopr.70253","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jopr.70253","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:17:49Z","timestamp":1791350269000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jopr.70253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,6]]},"references-count":50,"alternative-id":["10.1111\/jopr.70253"],"URL":"https:\/\/doi.org\/10.1111\/jopr.70253","archive":["Portico"],"relation":{},"ISSN":["1059-941X","1532-849X"],"issn-type":[{"value":"1059-941X","type":"print"},{"value":"1532-849X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,6]]},"assertion":[{"value":"2026-07-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"jopr.70253"}}