{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:33:01Z","timestamp":1777944781052,"version":"3.51.4"},"reference-count":66,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Renal Care"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Adults receiving hemodialysis experience many problems. Benson's relaxation technique has been used to manage these problems, but evidence of its effectiveness is limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess Benson's relaxation effects on physical, psychological outcomes, and quality of life in adults receiving hemodialysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Systematic review and meta\u2010analysis of randomized controlled trials registered in PROSPERO (CRD42022379551).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Adults receiving hemodialysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>Eleven databases were searched through January 18, 2024, and updated January 10, 2025. Eligible RCTs involved adults on hemodialysis for at least 3 months, comparing Benson's relaxation with routine care or other interventions. Primary outcomes included physical measures, quality of life, and psychological outcomes; secondary outcomes were narratively reported. Risk of bias was assessed with Cochrane RoB 2.0, and evidence certainty with GRADE. Random\u2010effects meta\u2010analysis and sensitivity analyses used Comprehensive Meta\u2010Analysis v3.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fourteen trials with 1,104 participants provided low\u2010certainty evidence for small effects on serum phosphate (Hedges'\n                      <jats:italic>g<\/jats:italic>\n                      \u2009=\u20090.39,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.010) and large effects on pain (Hedges'\n                      <jats:italic>g<\/jats:italic>\n                      \u2009=\u20091.21,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.010). Very\u2010low\u2010certainty evidence found moderate effects on quality of life (Hedges'\n                      <jats:italic>g<\/jats:italic>\n                      \u2009=\u20090.65,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.010) and large effects on stress (Hedges'\n                      <jats:italic>g<\/jats:italic>\n                      \u2009=\u20091.58,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.017). High\u2010certainty evidence showed small effects on anxiety (Hedges'\n                      <jats:italic>g<\/jats:italic>\n                      \u2009=\u20090.45,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). No significant effects were observed for serum calcium or depression symptoms. Sensitivity analyses showed variable robustness. Secondary outcomes were reported narratively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Overall, current evidence supports cautious clinical interpretation and highlights the need for further rigorous, adequately powered randomized controlled trials.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Registration<\/jats:title>\n                    <jats:p>This study is registered in PROSPERO (Registration Number: CRD42022379551, registered on December 8, 2022).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jorc.70043","type":"journal-article","created":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T07:55:45Z","timestamp":1768463745000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Benson's Relaxation on Physical, Psychological, and Quality of Life Outcomes in Adults Receiving Hemodialysis: Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9711-2620","authenticated-orcid":false,"given":"\u015eefika Tu\u011fba","family":"Yang\u00f6z","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Nursing, Faculty of Health Sciences Pamukkale University Denizli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4545-9945","authenticated-orcid":false,"given":"Zeynep","family":"Karaku\u015f","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Nursing, Faculty of Nursing Akdeniz University Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8405-1208","authenticated-orcid":false,"given":"Zeynep","family":"\u00d6zer","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Nursing, Faculty of Nursing Akdeniz University Antalya 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