{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:11:28Z","timestamp":1773706288022,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,12,2]],"date-time":"2012-12-02T00:00:00Z","timestamp":1354406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>The study aims to review the contemporary presentation, diagnosis and treatment of children with infantile hypertrophic pyloric stenosis (<jats:styled-content style=\"fixed-case\">IHPS<\/jats:styled-content>) at an Australian paediatric tertiary centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective case review of patients with <jats:styled-content style=\"fixed-case\">IHPS<\/jats:styled-content> presenting to our institution between <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2004 and <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2010 was performed. Results were compared with a previous study evaluating two earlier 6\u2010year series of patients treated between <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 1984 and <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ovember 1995.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 362 infants presenting over the current 7\u2010year review, 84.8% were male. Mean age of admission fell from 5.9 weeks in the previous study to 5.4 weeks. An \u2018olive\u2019 was palpated on examination in 48%, visible peristalsis seen in 25% and 16% of patients presented with haematemesis. Diagnosis solely on clinical examination fell from 74% to 9% and was associated with a corresponding increase in use of ultrasound from 16% to 91%. The frequency of serum chloride values less than 85\u2009mmol\/L declined from 26% to 9%. A variety of open and minimally invasive surgical approaches were used with similar outcomes, although laparoscopic pyloromyotomy was associated with significantly higher rates of wound infection (\u03c7<jats:sup>2<\/jats:sup>\u2009=\u20094.6, <jats:italic>P<\/jats:italic>\u2009=\u20090.03). The frequency of major complications remained low at 1%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Contemporary patients with <jats:styled-content style=\"fixed-case\">IHPS<\/jats:styled-content> typically present earlier with a reduction in the incidence of metabolic derangement. Diagnosis based on clinical examination alone appears uncommon, with the majority of suspected cases confirmed by ultrasound. There was no clear difference in overall outcome based on the surgical approach used, although minor variations may reflect our institution's initial experience with laparoscopic pyloromyotomy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12027","type":"journal-article","created":{"date-parts":[[2012,12,3]],"date-time":"2012-12-03T08:51:46Z","timestamp":1354524706000},"page":"33-37","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":62,"title":["Infantile hypertrophic pyloric stenosis: Has anything changed?"],"prefix":"10.1111","volume":"49","author":[{"given":"Nicole D","family":"Taylor","sequence":"first","affiliation":[{"name":"Douglas Cohen Department of Paediatric Surgery The Children's Hospital at Westmead Sydney Medical School The University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel T","family":"Cass","sequence":"additional","affiliation":[{"name":"Douglas Cohen Department of Paediatric Surgery The Children's Hospital at Westmead Sydney Medical School The University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew JA","family":"Holland","sequence":"additional","affiliation":[{"name":"Douglas Cohen Department of Paediatric Surgery The Children's Hospital at Westmead Sydney Medical School The University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,12,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(96)90032-9"},{"key":"e_1_2_8_3_1","first-page":"713","volume-title":"Practical Paediatrics","author":"Beasley SW","year":"2007"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-6757(99)90020-7"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-6723.2009.01218.x"},{"key":"e_1_2_8_6_1","first-page":"36","article-title":"Infantile hypertrophic pyloric stenosis: experience in a district general hospital","volume":"35","author":"Saunders MP","year":"1990","journal-title":"J. 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