{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T06:55:28Z","timestamp":1758264928274},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,1,21]],"date-time":"2013-01-21T00:00:00Z","timestamp":1358726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>The aim of this study is to investigate the health\u2010related quality of life in children with severe lower limb trauma after at least 12 months post\u2010injury and to assess patient and injury characteristics in association with the health\u2010related quality of life scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All children in the state of Victoria, who were 18 years of age or younger, suffering from severe lower limb injury before 2006 were studied. Patient and injury characteristics were abstracted from medical records. The health\u2010related quality of life (<jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content>) scores were obtained using the <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>aediatric <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>uality of Life Inventory.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010two out of 64 eligible patients participated in this study. All aspects of health\u2010related quality of life in children with severe lower limb trauma after at least 12 months post\u2010injury were significantly poorer compared with non\u2010affected children, particularly in the physical health domain (difference: \u221212.51 \u00b1 7.43: <jats:italic>P<\/jats:italic> &lt; 0.05). It was observed that bilateral limb involvement and the need for soft tissue management were related to poor physical functioning (<jats:italic>P<\/jats:italic> &lt; 0.05). Other characteristics such as traumatic amputation, gender, growth plate injury, joint bony injury and accident mechanism did not affect the overall <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content> scores (<jats:italic>P<\/jats:italic> &gt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content> in children with severe lower limb trauma was significantly impaired even after 12 months post\u2010injury, notably in patient group with bilateral limb involvement and need for soft tissue management. Traumatic amputation, gender, growth plate injury, joint bony injury and accident mechanism did not have an impact on quality of life.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12090","type":"journal-article","created":{"date-parts":[[2013,1,21]],"date-time":"2013-01-21T11:54:39Z","timestamp":1358769279000},"page":"131-137","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cross\u2010sectional study to investigate the health\u2010related quality of life in children with severe lower limb trauma in <scp>V<\/scp>ictoria"],"prefix":"10.1111","volume":"49","author":[{"given":"Aik H","family":"Lim","sequence":"first","affiliation":[{"name":"Melbourne University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damon","family":"Thomas","sequence":"additional","affiliation":[{"name":"Departments of Plastic Surgery  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerr H","family":"Graham","sequence":"additional","affiliation":[{"name":"Orthopaedics The Royal Children Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,1,21]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1097\/00003086-199007000-00013","article-title":"Limb salvage versus amputation: preliminary results of the mangled extremity severity score","volume":"256","author":"Helfet DL","year":"1990","journal-title":"Clin. 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