{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T13:42:31Z","timestamp":1759412551655},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,1,22]],"date-time":"2013-01-22T00:00:00Z","timestamp":1358812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"CSL Vaccines"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2013,2]]},"abstract":"Aim<\/jats:title>Acute gastroenteritis (AGE<\/jats:styled-content>) has been a significant component of the clinical load in the short stay unit (SSU<\/jats:styled-content>) at the R<\/jats:styled-content>oyal C<\/jats:styled-content>hildren's H<\/jats:styled-content>ospital (RCH<\/jats:styled-content>) since its establishment in 2004. Since the introduction of routine rotavirus immunisation in A<\/jats:styled-content>ustralia in 2007 there has been a clinical impression of a substantial reduction in AGE<\/jats:styled-content> managed in the SSU<\/jats:styled-content>. This study aimed to examine changes in the epidemiology of AGE<\/jats:styled-content> in the SSU<\/jats:styled-content>, and RCH<\/jats:styled-content> overall, between 2005 and 2009 and explore whether this reflects a change specifically in AGE<\/jats:styled-content> due to rotavirus.<\/jats:p><\/jats:sec>Methods<\/jats:title>Discharge coding data for AGE<\/jats:styled-content> from all inpatient wards, the SSU<\/jats:styled-content> and emergency department (ED<\/jats:styled-content>) at the RCH<\/jats:styled-content> were examined. Stool virology results for the same period were analysed.<\/jats:p><\/jats:sec>Results<\/jats:title>Since 2007 there has been a 58% reduction in AGE<\/jats:styled-content> admissions to the SSU<\/jats:styled-content>. The median age of patients admitted to the RCH<\/jats:styled-content> with rotaviral enteritis has increased from 1.3 years to 3.8 years. Presentations to the ED<\/jats:styled-content> for AGE<\/jats:styled-content> have fallen from 53 to 34 cases per 1000 attendances between 2004 and 2009, and admission rates from the ED<\/jats:styled-content> have fallen from 23 to 13% of AGE<\/jats:styled-content> presentations. Detection rates of rotavirus fell from 13.1 to 6.7% between 2005 and 2009.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>A marked decrease in AGE<\/jats:styled-content>\u2010related clinical activity and reduction in rotavirus detection at the RCH<\/jats:styled-content> has occurred since the introduction of routine rotavirus immunisation in A<\/jats:styled-content>ustralia. This has significant resource planning implications for units based on short stay models of care.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12098","type":"journal-article","created":{"date-parts":[[2013,1,22]],"date-time":"2013-01-22T08:59:29Z","timestamp":1358845169000},"page":"120-124","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Changes in the epidemiology of gastroenteritis in a paediatric short stay unit following the introduction of rotavirus immunisation"],"prefix":"10.1111","volume":"49","author":[{"given":"Jonathan D","family":"Akikusa","sequence":"first","affiliation":[{"name":"Department of General Medicine Royal Children's Hospital Melbourne Victoria Australia"},{"name":"Murdoch Children's Research Institute Monash Children's Hospital, Monash University Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandy M","family":"Hopper","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Royal Children's Hospital Melbourne Victoria Australia"},{"name":"Murdoch Children's Research Institute Monash Children's Hospital, Monash University Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian J","family":"Kelly","sequence":"additional","affiliation":[{"name":"Department of General Medicine Royal Children's Hospital Melbourne Victoria Australia"},{"name":"Department of Paediatrics, University of Melbourne Royal Children's Hospital Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl D","family":"Kirkwood","sequence":"additional","affiliation":[{"name":"Enteric Virus Research Group Monash Children's Hospital, Monash University Melbourne Victoria Australia"},{"name":"Infectious Diseases Unit Department of Paediatrics Monash Children's Hospital, Monash University Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim P","family":"Buttery","sequence":"additional","affiliation":[{"name":"Department of General Medicine Royal Children's Hospital Melbourne Victoria Australia"},{"name":"Murdoch Children's Research Institute Monash Children's Hospital, Monash University Melbourne Victoria Australia"},{"name":"Infectious Diseases Unit Department of Paediatrics Monash Children's Hospital, Monash University Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,1,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.83.4.369f"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006565-200110000-00001"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-6723.2008.01112.x"},{"key":"e_1_2_7_5_1","first-page":"337","article-title":"Rotavirus vaccination one year on","volume":"33","author":"Belshaw DA","year":"2009","journal-title":"Commun. 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