{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T13:41:10Z","timestamp":1774014070129,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,26]],"date-time":"2013-02-26T00:00:00Z","timestamp":1361836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Victorian Government's Operational Infrastructure Support Program"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>To examine sleep study findings in children with <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>rader\u2013<jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>illi syndrome (<jats:styled-content style=\"fixed-case\">PWS<\/jats:styled-content>) referred for polysomnography (<jats:styled-content style=\"fixed-case\">PSG<\/jats:styled-content>) before commencement of growth hormone (<jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content>) and to evaluate the impact of sleep testing on treatment decisions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The sleep unit database was used to identify all cases over an 8\u2010year period (2003\u20132011). Standard overnight <jats:styled-content style=\"fixed-case\">PSG<\/jats:styled-content> was performed in the sleep laboratory. Obstructive sleep apnoea (<jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>) was defined by an obstructive apnoea\u2013hypopnoea index &gt;1\/h. Age, symptoms of <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>, tonsillar size and body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>) <jats:styled-content style=\"fixed-case\">Z<\/jats:styled-content>\u2010score were obtained through chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> was diagnosed in 15 of 34 (44%) cases identified. Those with <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> were significantly older (<jats:italic>P<\/jats:italic> = 0.009) and more likely to have enlarged tonsils (<jats:italic>P<\/jats:italic> = 0.05) than those without <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>. There was no difference in <jats:styled-content style=\"fixed-case\">BMI Z<\/jats:styled-content>\u2010score or the presence of symptoms of <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content> was deferred in 13 (38%) pending treatment for <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> was frequently present in children with <jats:styled-content style=\"fixed-case\">PWS<\/jats:styled-content> referred simply to meet the requirement for <jats:styled-content style=\"fixed-case\">PSG<\/jats:styled-content> before starting <jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> was more likely in older children and those with enlarged tonsils. <jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content> treatment was deferred in 38% of cases. This study supports routine performance of <jats:styled-content style=\"fixed-case\">PSG<\/jats:styled-content> prior to <jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content>, regardless of clinical history.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12109","type":"journal-article","created":{"date-parts":[[2013,2,26]],"date-time":"2013-02-26T12:08:55Z","timestamp":1361880535000},"page":"238-241","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Are sleep studies helpful in children with <scp>P<\/scp>rader\u2013<scp>W<\/scp>illi syndrome prior to commencement of growth hormone therapy?"],"prefix":"10.1111","volume":"49","author":[{"given":"Moya","family":"Vandeleur","sequence":"first","affiliation":[{"name":"Melbourne Children's Sleep Centre Monash Children's Monash Medical Centre  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margot J","family":"Davey","sequence":"additional","affiliation":[{"name":"Melbourne Children's Sleep Centre Monash Children's Monash Medical Centre  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gillian M","family":"Nixon","sequence":"additional","affiliation":[{"name":"Melbourne Children's Sleep Centre Monash Children's Monash Medical Centre  Melbourne Victoria Australia"},{"name":"The Ritchie Centre Monash Institute of Medical Research Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,2,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1994.77.5.2224"},{"key":"e_1_2_9_3_1","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1542\/peds.91.2.398","article-title":"Prader\u2010Willi syndrome: consensus diagnostic criteria","volume":"91","author":"Holm VA","year":"1993","journal-title":"Paediatrics"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004310050555"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20673"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(99)70418-X"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0765"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004310051246"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021536"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32131"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.20371"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.30777"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2005.tb02022.x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03347245"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2003.09.049"},{"key":"e_1_2_9_16_1","unstructured":"Australian Government Department of Health and Aging.Guidelines for the Pharmaceutical Benefits Scheme Growth Hormone Program (April 2012) 2012. Available from:http:\/\/www.health.gov.au\/hgh. [accessed 22 November 2011]."},{"key":"e_1_2_9_17_1","unstructured":"USDA\/ARS Children's Nutrition Research Centre.Children's BMI\u2010percentile\u2010for\u2010age Calculator 2007. Available from:http:\/\/www.bcm.edu\/cnrc\/bodycomp\/bmiz2.html. [accessed 17 January 2011]."},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.153.2.8564147"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2002.123290"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.10152"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-1279"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.120.6.1930"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2008.07.058"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-1445"}],"container-title":["Journal of Paediatrics and Child Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjpc.12109","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjpc.12109","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jpc.12109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T04:28:36Z","timestamp":1697344116000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jpc.12109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,26]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1111\/jpc.12109"],"URL":"https:\/\/doi.org\/10.1111\/jpc.12109","archive":["Portico"],"relation":{},"ISSN":["1034-4810","1440-1754"],"issn-type":[{"value":"1034-4810","type":"print"},{"value":"1440-1754","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,26]]},"assertion":[{"value":"2012-06-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-02-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}