{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T03:07:39Z","timestamp":1789614459240,"version":"build-2803163510"},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,3,29]],"date-time":"2013-03-29T00:00:00Z","timestamp":1364515200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Cardiac arrhythmias are an important cause of morbidity in infants. Although the spectrum of types of arrhythmia has been reported, there has been no previous population\u2010based study of the incidence of arrhythmias in infancy. Our aim was to define the population incidence of arrhythmia in infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We based this study on the Northern Region of <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>ngland with a resident population of 3.1 million and an annual live birth rate of 33\u2009000. We identified all clinically significant arrhythmias in infants in 1991\u20132010 from the regional cardiac database. All diagnoses were based on analysis of the electrocardiogram. Infants with only the substrate for arrhythmia (such as <jats:styled-content style=\"fixed-case\">QT<\/jats:styled-content> prolongation or ventricular pre\u2010excitation) were excluded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 20 years, there were 662\u2009698 live births. We identified 162 cases of newly diagnosed arrhythmia of which 22 had associated structural cardiovascular malformations. The incidence of arrhythmia was 24.4 per 100\u2009000 live births. The most common arrhythmia was atrioventricular re\u2010entry tachycardia with an incidence of 16.3 per 100\u2009000. Complete atrioventricular block and atrial flutter both occurred at 2.1 cases per 100\u2009000 live births, and other arrhythmias were rare.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study is the first to report a population incidence of arrhythmia in infants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12155","type":"journal-article","created":{"date-parts":[[2013,3,29]],"date-time":"2013-03-29T09:36:37Z","timestamp":1364549797000},"page":"278-281","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":62,"title":["The epidemiology of arrhythmia in infants: A population\u2010based study"],"prefix":"10.1111","volume":"49","author":[{"given":"Christian James","family":"Turner","sequence":"first","affiliation":[{"name":"The Heart Centre for Children The Children's Hospital at Westmead  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Wren","sequence":"additional","affiliation":[{"name":"Freeman Hospital  Newcastle upon Tyne United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,3,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01886-7"},{"key":"e_1_2_8_3_1","first-page":"127","article-title":"Definition of terms related to cardiac rhythm. 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