{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T07:49:55Z","timestamp":1743320995294,"version":"3.37.3"},"reference-count":45,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,6,18]],"date-time":"2013-06-18T00:00:00Z","timestamp":1371513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NHMRC H1N1","award":["633028"],"award-info":[{"award-number":["633028"]}]},{"DOI":"10.13039\/501100000276","name":"NSW Department of Health","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000276","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Commonwealth Department of Health and Ageing"},{"name":"DoHA"},{"name":"NHMRC Enabling","award":["402784"],"award-info":[{"award-number":["402784"]}]},{"name":"NHMRC Practitioner Fellowship","award":["021480"],"award-info":[{"award-number":["021480"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2013,8]]},"abstract":"Aims<\/jats:title>To document risk factors, clinical features and outcomes in infants <6 months old admitted with laboratory\u2010confirmed influenza to The C<\/jats:styled-content>hildren's H<\/jats:styled-content>ospital at W<\/jats:styled-content>estmead during the H<\/jats:styled-content>1N<\/jats:styled-content>1\u201009 pandemic.<\/jats:p><\/jats:sec>Methods<\/jats:title>Prospective, hospital\u2010based case series of infants admitted J<\/jats:styled-content>une\u2013S<\/jats:styled-content>eptember 2009, identified by the P<\/jats:styled-content>aediatric A<\/jats:styled-content>ctive E<\/jats:styled-content>nhanced D<\/jats:styled-content>isease S<\/jats:styled-content>urveillance system and supplemented by telephone interview post\u2010discharge.<\/jats:p><\/jats:sec>Results<\/jats:title>Thirty\u2010two infants <6 months old had influenza A<\/jats:styled-content>: 18 H<\/jats:styled-content>1N<\/jats:styled-content>1\u201009, 11 H<\/jats:styled-content>3N<\/jats:styled-content>2 and three unknown subtypes. After discharge, 28 (88%) families were telephoned and provided additional information. Documented risk factors included close contact with young children (46%), living with a smoker (36%), intensive or special care at birth (25%), pre\u2010existing illness (16%) and preterm birth (14%). The number of persons per household was double the state average. Only 14% of mothers were vaccinated against seasonal influenza. Infants commonly presented with cough (69%), coryza (69%), lethargy (38%), fever (31%), dyspnoea (31%) and vomiting (28%). Complications included pneumonia (22%), and bacterial (9%) and viral (6%) co\u2010infection. Five infants (15%) required admission to intensive care, and one was mechanically ventilated. Sixteen (57%) had ongoing respiratory problems, and six (21%) presented to the E<\/jats:styled-content>mergency D<\/jats:styled-content>epartment within 6 months of discharge.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>These novel data are clinically important. Rates of influenza in infants may be reduced by vaccinating close contacts and minimising exposure to infected contacts and cigarette smoke.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12266","type":"journal-article","created":{"date-parts":[[2013,6,19]],"date-time":"2013-06-19T11:47:38Z","timestamp":1371642458000},"page":"635-640","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Influenza infection in infants aged <6 months during the H<\/scp>1N<\/scp>1\u201009 pandemic: A hospital\u2010based case series"],"prefix":"10.1111","volume":"49","author":[{"given":"Emilia E","family":"Esterman","sequence":"first","affiliation":[{"name":"Postgraduate Medical Program Sydney Medical School Westmead New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica M","family":"Lahra","sequence":"additional","affiliation":[{"name":"WHO Collaborating Centre Microbiology Department SEALS The Prince of Wales Hospital Westmead New South Wales Australia"},{"name":"Faculty of Medicine School of Medical Sciences The University of NSW Westmead New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yvonne A","family":"Zurynski","sequence":"additional","affiliation":[{"name":"Discipline of Paediatrics and Child Health Sydney Medical School The University of Sydney Westmead New South Wales Australia"},{"name":"Australian Paediatric Surveillance Unit Westmead New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Booy","sequence":"additional","affiliation":[{"name":"Discipline of Paediatrics and Child Health Sydney Medical School The University of Sydney Westmead New South Wales Australia"},{"name":"National Centre for Immunisation Research and Surveillance Westmead New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth J","family":"Elliott","sequence":"additional","affiliation":[{"name":"Discipline of Paediatrics and Child Health Sydney Medical School The University of Sydney Westmead New South Wales Australia"},{"name":"Australian Paediatric Surveillance Unit Westmead New South Wales Australia"},{"name":"Department of Medicine The Children's Hospital at Westmead Westmead New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,6,18]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"ChanM.World now at the start of 2009 influenza pandemic.2009. 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