{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:13:34Z","timestamp":1787015614038,"version":"build-2736575974"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,6,19]],"date-time":"2013-06-19T00:00:00Z","timestamp":1371600000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001027","name":"Australian Government Department of Health and Ageing","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001027","id-type":"DOI","asserted-by":"crossref"}]},{"name":"NHMRC Enabling","award":["402784"],"award-info":[{"award-number":["402784"]}]},{"name":"NHMRC Practitioner Fellowships","award":["457084"],"award-info":[{"award-number":["457084"]}]},{"name":"NHMRC Practitioner Fellowships","award":["1021480"],"award-info":[{"award-number":["1021480"]}]},{"name":"The Creswick Foundation Fellowship"},{"name":"Faculty of Medicine, University of Sydney"},{"DOI":"10.13039\/501100001232","name":"Royal Australasian College of Physicians","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001232","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The Paediatric Active Enhanced Disease Surveillance (PAEDS) is described. PAEDS is active in four tertiary children's hospitals in four states of Australia and aims to address gaps in surveillance for severe vaccine\u2010preventable diseases and adverse events following immunisation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      From\n                      <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\n                      ugust 2007 to\n                      <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>\n                      ecember 2010, surveillance nurses actively identified and recruited children admitted with: acute flaccid paralysis, varicella infection, intussusception, seizures in infants and pandemic influenza (\n                      <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>\n                      une\u2013\n                      <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>\n                      ctober 2009). Details of presentation, medical and immunisation history, outcome and laboratory results were collected. Completeness of ascertainment was estimated through audits of International Classification of Diseases 10th edition\u2010coded medical records where possible.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seven hundred thirty\u2010three cases matching case definition criteria for the four conditions were recruited. In addition, 601 cases of influenza were recruited during the 2009 pandemic.\n                      <jats:styled-content style=\"fixed-case\">PAEDS<\/jats:styled-content>\n                      enhanced acute flaccid paralysis surveillance by the\n                      <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\n                      ustralian\n                      <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\n                      aediatric\n                      <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                      urveillance\n                      <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>\n                      nit; the\n                      <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>\n                      orld\n                      <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>\n                      ealth\n                      <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>\n                      rganization surveillance target was met when\n                      <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\n                      ustralian\n                      <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\n                      aediatric\n                      <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                      urveillance\n                      <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>\n                      nit and\n                      <jats:styled-content style=\"fixed-case\">PAEDS<\/jats:styled-content>\n                      cases were combined. Among 133 children hospitalised for varicella, only 16 were vaccinated; samples of vesicle scrapings were collected in 57% for genotyping. Of 122 infants presenting with seizures, only six (12%) had received a vaccine in the last 7 days. Intussusception was more frequent among infants receiving their first dose of either of the rotavirus vaccines. Results informed policy and education for parents and health professionals. Preliminary audits of medical records suggest excellent ascertainment through\n                      <jats:styled-content style=\"fixed-case\">PAEDS<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">PAEDS<\/jats:styled-content>\n                      provides important, previously unavailable data to inform public health policy, clinical practice and community confidence. It has potential to respond quickly during outbreaks and epidemics.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jpc.12282","type":"journal-article","created":{"date-parts":[[2013,6,19]],"date-time":"2013-06-19T08:05:44Z","timestamp":1371629144000},"page":"588-594","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["<scp>P<\/scp>\n                    aediatric\n                    <scp>A<\/scp>\n                    ctive\n                    <scp>E<\/scp>\n                    nhanced\n                    <scp>D<\/scp>\n                    isease\n                    <scp>S<\/scp>\n                    urveillance: A new surveillance system for\n                    <scp>A<\/scp>\n                    ustralia"],"prefix":"10.1111","volume":"49","author":[{"given":"Yvonne","family":"Zurynski","sequence":"first","affiliation":[{"name":"Australian Paediatric Surveillance Unit  Sydney New South Wales Australia"},{"name":"The Discipline of Paediatrics and Child Health, Sydney Medical School The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"McIntyre","sequence":"additional","affiliation":[{"name":"National Centre for Immunisation Research and Surveillance Kids Research Institute  Sydney New South Wales Australia"},{"name":"The Sydney Children's Hospitals Network (Randwick and Westmead)  Sydney New South Wales Australia"},{"name":"The Discipline of Paediatrics and Child Health, Sydney Medical School The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Booy","sequence":"additional","affiliation":[{"name":"National Centre for Immunisation Research and Surveillance Kids Research Institute  Sydney New South Wales Australia"},{"name":"The Sydney Children's Hospitals Network (Randwick and Westmead)  Sydney New South Wales Australia"},{"name":"The Discipline of Paediatrics and Child Health, Sydney Medical School The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth J","family":"Elliott","sequence":"additional","affiliation":[{"name":"Australian Paediatric Surveillance Unit  Sydney New South Wales Australia"},{"name":"The Sydney Children's Hospitals Network (Randwick and Westmead)  Sydney New South Wales Australia"},{"name":"The Discipline of Paediatrics and Child Health, Sydney Medical School The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"PAEDS Investigators Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,19]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"81","article-title":"Surveillance systems reported in CDI","volume":"34","author":"Health Protection and Surveillance Branch, Office of Health Protection, Australian Government Department of Health and Ageing","year":"2010","journal-title":"Commun. Dis. Intell."},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1045-1870(03)00036-0"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1093\/pch\/14.1.33","article-title":"IMPACT after 17 years: lessons learned about successful networking","volume":"14","author":"Scheifele D","year":"2009","journal-title":"J. Paediatr. Child Health"},{"key":"e_1_2_8_5_1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.33321\/cdi.2010.34.27","article-title":"Annual report of the Australian National Poliovirus Reference Laboratory, 2009","volume":"34","author":"Roberts JA","year":"2010","journal-title":"Commun. Dis. Intell."},{"key":"e_1_2_8_6_1","unstructured":"World Health Organisation.WHO\u2010recommended standards for surveillance of selected vaccine\u2010preventable diseases2003. Available from:http:\/\/www.who.int\/vaccines\u2010documents\/DocsPDF06\/843.pdf[accessed March 2012]."},{"key":"e_1_2_8_7_1","volume-title":"The Australian Immunisation Handbook","author":"National Health and Medical Research Council","year":"2008"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2006.00949.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200102223440804"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1586\/erv.09.106"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2011.02240.x"},{"key":"e_1_2_8_12_1","unstructured":"WHO Global Advisory Committee on Vaccine Safety.Safety of pandemic A(H1N1) influenza vaccines.2009. Available from:http:\/\/www.who.int\/vaccine_safety\/topics\/influenza\/pandemic\/%20h1n1_safety_assessing\/Dec_2009\/en\/[accessed June 2012]."},{"key":"e_1_2_8_13_1","doi-asserted-by":"crossref","first-page":"285","DOI":"10.33321\/cdi.2010.34.28","article-title":"Australian paediatric surveillance unit annual report, 2008 and 2009","volume":"34","author":"Zurynski Y","year":"2010","journal-title":"Commun. Dis. Intell."},{"key":"e_1_2_8_14_1","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.33321\/cdi.2008.32.9","article-title":"Enhanced surveillance for serious complications of influenza in children: role of the Australian Paediatric Surveillance Unit","volume":"32","author":"Zurynski Y","year":"2008","journal-title":"Commun. Dis. Intell."},{"key":"e_1_2_8_15_1","unstructured":"NSW Parliament.Health Records and Information Privacy Act 2002. Available from:%20http:\/\/www.legislation.nsw.gov.au\/fullhtml\/%20inforce\/act+71+2002+FIRST+0+N[accessed March 2011]."},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.01.088"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31827e92b7"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1012952"},{"key":"e_1_2_8_19_1","unstructured":"Australian Government Department of Health and Ageing Immunise Australia Program.Rotavirus vaccine and intussusception: information for parents February2011. Available from:http:\/\/immunise.health.gov.au\/internet\/%20immunise\/publishing.nsf\/Content\/ITO137\u2010cnt[accessed June 2012]."},{"key":"e_1_2_8_20_1","unstructured":"Australian Government Department of Health and Ageing Therapeutic Goods Administration.Rotavirus vaccination and risk of intussusception: a report of TGA's investigation of a possible safety signal. 25 February2011 Available from:http:\/\/www.tga.gov.au\/%20safety\/alerts\u2010medicine\u2010rotavirus\u2010110225.htm[accessed June 2012]."},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2010-000016"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1071\/NB10031"},{"key":"e_1_2_8_23_1","first-page":"35","article-title":"Updated guidelines for evaluating public health surveillance systems","volume":"50","author":"Centers for Disease","year":"2001","journal-title":"MMWR Recomm. Rep."}],"container-title":["Journal of Paediatrics and Child Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjpc.12282","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjpc.12282","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jpc.12282","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,20]],"date-time":"2025-07-20T14:12:33Z","timestamp":1753020753000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jpc.12282"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,19]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.1111\/jpc.12282"],"URL":"https:\/\/doi.org\/10.1111\/jpc.12282","archive":["Portico"],"relation":{},"ISSN":["1034-4810","1440-1754"],"issn-type":[{"value":"1034-4810","type":"print"},{"value":"1440-1754","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,19]]},"assertion":[{"value":"2012-12-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-06-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}