{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:01:27Z","timestamp":1790352087601,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2013,6,18]],"date-time":"2013-06-18T00:00:00Z","timestamp":1371513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2013,10]]},"abstract":"Aim<\/jats:title>A nationwide 24\u2010month study was conducted (2007\u20132009), via the New Zealand Paediatric Surveillance Unit to define epidemiology and clinical features of acute poststreptococcal glomerulonephritis (APSGN) in children hospitalised with the illness.<\/jats:p><\/jats:sec>Methods<\/jats:title>Paediatricians (n<\/jats:italic> = 215) were requested to report new hospitalised cases fulfilling a case definition of definite (haematuria with low C3 and high streptococcal titres or biopsy proven APSGN<\/jats:styled-content>) or probable (haematuria with low C<\/jats:styled-content>3 or high streptococcal titres).<\/jats:p><\/jats:sec>Results:\u2003<\/jats:title>A total of 176 cases were identified (definite: n<\/jats:italic> = 138, probable: n<\/jats:italic> = 38) with 63% residing in the A<\/jats:styled-content>uckland metropolitan region. Sixty\u2010seven percent were in the most deprived quintile. Annual incidence (0\u201314 years) was 9.7\/100\u2009000 (P<\/jats:styled-content>acific 45.5, M<\/jats:styled-content>aori 15.7, E<\/jats:styled-content>uropean\/other 2.6 and A<\/jats:styled-content>sian 2.1\/100\u2009000). Annual incidence was highest in the S<\/jats:styled-content>outh A<\/jats:styled-content>uckland M<\/jats:styled-content>etropolitan region (31\/100\u2009000), C<\/jats:styled-content>entral A<\/jats:styled-content>uckland 14.9, W<\/jats:styled-content>est\/N<\/jats:styled-content>orth A<\/jats:styled-content>uckland metropolitan region 5.9 and for the remainder of N<\/jats:styled-content>ew Z<\/jats:styled-content>ealand 5.5\/100\u2009000. Age\u2010specific incidence was highest in age 5\u20139 years (15.1\/100\u2009000). Reduced serum complement C<\/jats:styled-content>3, gross haematuria, hypertension, impairment of renal function and heavy proteinuria were present in 93%, 87%, 72%, 67% and 44% of patients, respectively. Severe hypertension was closely associated with either symptoms of an acute encephalopathy or congestive heart failure.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>N<\/jats:styled-content>ew Z<\/jats:styled-content>ealand children carry a significant disease burden of hospitalised APSGN<\/jats:styled-content> with socio\u2010economically deprived; P<\/jats:styled-content>acific and M<\/jats:styled-content>aori children are being over\u2010represented. Significant short\u2010term complications were observed in hospitalised children with APSGN<\/jats:styled-content>. Persistently very low rates in E<\/jats:styled-content>uropean\/other suggest a preventable disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12295","type":"journal-article","created":{"date-parts":[[2013,6,19]],"date-time":"2013-06-19T11:52:16Z","timestamp":1371642736000},"page":"850-855","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Prospective population\u2010based study on the burden of disease from post\u2010streptococcal glomerulonephritis of hospitalised children in N<\/scp>ew Z<\/scp>ealand: Epidemiology, clinical features and complications"],"prefix":"10.1111","volume":"49","author":[{"given":"William","family":"Wong","sequence":"first","affiliation":[{"name":"Department of Paediatric Nephrology Starship Children's Hospital Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana R","family":"Lennon","sequence":"additional","affiliation":[{"name":"School of Population Health University of Auckland Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"Crone","sequence":"additional","affiliation":[{"name":"Department of Paediatric Nephrology Starship Children's Hospital Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocelyn M","family":"Neutze","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Kidz First Hospital Middlemore Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter W","family":"Reed","sequence":"additional","affiliation":[{"name":"Children's Research Unit Starship Children's Health Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-008-1086-5"},{"issue":"847","key":"e_1_2_8_3_1","first-page":"396","article-title":"Longitudinal study of poststreptococcal disease in Auckland; rheumatic fever, glomerulonephritis, epidemiology and M typing 1981\u201386","volume":"101","author":"Lennon D","year":"1988","journal-title":"N. 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