{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:10:26Z","timestamp":1791814226065,"version":"4.3.4"},"reference-count":41,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2013,6,27]],"date-time":"2013-06-27T00:00:00Z","timestamp":1372291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2013,10]]},"abstract":"\n Aim<\/jats:title>\n \n To determine whether, in children with congenital heart disease (\n CHD<\/jats:styled-content>\n ), disease severity is associated with health\u2010related quality of life (\n HRQOL<\/jats:styled-content>\n ) and impact on the family.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Cross\u2010sectional, single\u2010centre study comparing\n HRQOL<\/jats:styled-content>\n outcomes of age and sex matched children with hypoplasia of the left ventricle (\n HLV<\/jats:styled-content>\n ) (\n n<\/jats:italic>\n = 31) and tetralogy of\n F<\/jats:styled-content>\n allot (\n n<\/jats:italic>\n = 29) was performed in\n Q<\/jats:styled-content>\n ueensland,\n A<\/jats:styled-content>\n ustralia.\n HRQOL<\/jats:styled-content>\n was assessed using generic and disease\u2010specific components of the\n P<\/jats:styled-content>\n aediatric\n Q<\/jats:styled-content>\n uality of\n L<\/jats:styled-content>\n ife\n I<\/jats:styled-content>\n nventory\n M<\/jats:styled-content>\n easurement\n M<\/jats:styled-content>\n odel (PedsQL). Intra\u2010diagnostic age group comparisons of\n HRQOL<\/jats:styled-content>\n were examined. Impact of\n CHD<\/jats:styled-content>\n on families and parental\n HRQOL<\/jats:styled-content>\n was assessed using the PedsQL Family Impact Scale.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Child and parent\u2010proxy reporting indicate children with\n HLV<\/jats:styled-content>\n have significantly lower overall\n HRQOL<\/jats:styled-content>\n than children with tetralogy of Fallot across generic domains of\n HRQOL<\/jats:styled-content>\n (\n P<\/jats:italic>\n < 0.0001), with significantly lower scores in physical (\n P<\/jats:italic>\n < 0.0001) and psychosocial (\n P<\/jats:italic>\n < 0.0001) health domains. No significant difference in child reporting across domains of the\n C<\/jats:styled-content>\n ardiac\n M<\/jats:styled-content>\n odule is evident. Parent\u2010proxy reporting indicates significantly lower scores on the symptom scales for children with\n HLV<\/jats:styled-content>\n (\n P<\/jats:italic>\n < 0.001), with greater cognitive problems (\n P<\/jats:italic>\n < 0.02) and perceived treatment anxiety (\n P<\/jats:italic>\n < 0.01). No significant differences in\n HRQOL<\/jats:styled-content>\n were identified between age groups.\n HLV<\/jats:styled-content>\n has a greater overall family impact, with significantly lower parental\n HRQOL<\/jats:styled-content>\n (\n P<\/jats:italic>\n = 0.0001) and family functioning (\n P<\/jats:italic>\n < 0.0001) summary scores.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n The more severe condition of\n HLV<\/jats:styled-content>\n is associated with poorer\n HRQOL<\/jats:styled-content>\n in some domains and has greater impact on parental\n HRQOL<\/jats:styled-content>\n and family functioning.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jpc.12296","type":"journal-article","created":{"date-parts":[[2013,6,27]],"date-time":"2013-06-27T04:47:23Z","timestamp":1372308443000},"page":"856-864","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Health\u2010related quality of life and congenital heart disease in\n A<\/scp>\n ustralia"],"prefix":"10.1111","volume":"49","author":[{"given":"Karen J","family":"Eagleson","sequence":"first","affiliation":[{"name":"Queensland Paediatric Cardiac Service Mater Health Services Brisbane Queensland Australia"},{"name":"School of Population Health University of Queensland Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert N","family":"Justo","sequence":"additional","affiliation":[{"name":"Queensland Paediatric Cardiac Service Mater Health Services Brisbane Queensland Australia"},{"name":"School of Paediatric Medicine University of Queensland Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert S","family":"Ware","sequence":"additional","affiliation":[{"name":"School of Population Health University of Queensland Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan G","family":"Johnson","sequence":"additional","affiliation":[{"name":"Queensland Paediatric Cardiac Service Mater Health Services Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances M","family":"Boyle","sequence":"additional","affiliation":[{"name":"School of Population Health University of Queensland Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,27]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"56","volume-title":"Heart, Stroke and Vascular Diseases, Australian Facts 2004","author":"Australian Institute of Health and Welfare","year":"2004"},{"key":"e_1_2_9_3_1","first-page":"48","volume-title":"Congenital Anomalies in Australia 2002\u20132003","author":"Abeywardana 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