{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T21:19:30Z","timestamp":1780694370760,"version":"3.54.1"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,10,6]],"date-time":"2013-10-06T00:00:00Z","timestamp":1381017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To report survival, morbidity and neurodevelopmental outcome in a cohort of extremely low birthweight infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective cohort study of all inborn infants born alive with birthweights \u2264500\u2009g \u226522 weeks gestation at <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>omen's and <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hildren's <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital, <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>delaide, <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia, over a 6\u2010year period (2005\u20132010). Outcome data including standardised medical and psychological assessments at 12 and 36 months corrected age were collated from follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 36 eligible infants were born over the study period (mean gestational age (<jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content>) 24.4 (range 22.0\u201330.0) weeks; birthweight 443 (330\u2013500) grams). Twenty\u2010six of the 36 (72%) infants were small for gestational age (<jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>).Ten of the 36 infants received compassionate care and died in the delivery or operating room. Twenty\u2010six of the 36 infants were admitted to the neonatal intensive care unit (<jats:styled-content style=\"fixed-case\">NICU<\/jats:styled-content>), of whom 12 (46%) died during their admission. At age 12 months corrected, 2\/14 (14%) of survivors had none\/minimal, 4\/14 (29%) had mild and 8\/14 (57%) had moderate\/severe neurodevelopmental disability. Overall, the survival rate was 39%, and survival without neurodevelopmental disability was 6%. Only 1\/10 appropriate\u2010for\u2010gestational\u2010age (<jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content>) infants survived to discharge (and had severe disability), whereas 13\/26 (50%) of all <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> infants in the study survived to discharge. Of all infants admitted to the <jats:styled-content style=\"fixed-case\">NICU<\/jats:styled-content>, 11\/26 (42%) survived without severe neurodevelopmental disability at latest follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was a high risk of death or impairment in this cohort of infants. Survival was rare for <jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content> infants weighing \u2264500\u2009g at birth. Our study provides an evidence base to assist counselling and decision\u2010making.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12414","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T03:26:23Z","timestamp":1392607583000},"page":"146-152","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Beyond the borderline: Outcomes for inborn infants born at \u2264500 grams"],"prefix":"10.1111","volume":"50","author":[{"given":"Amy","family":"Keir","sequence":"first","affiliation":[{"name":"Department of Neonatal Medicine Women's and Children's Hospital Network  Adelaide Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"McPhee","sequence":"additional","affiliation":[{"name":"Department of Neonatal Medicine Women's and Children's Hospital Network  Adelaide Australia"},{"name":"Robinson Institute University of Adelaide  Adelaide Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominic","family":"Wilkinson","sequence":"additional","affiliation":[{"name":"Department of Neonatal Medicine Women's and Children's Hospital Network  Adelaide Australia"},{"name":"Robinson Institute University of Adelaide  Adelaide Australia"},{"name":"Oxford Uehiro Centre for Practical Ethics University of Oxford  Oxford United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2010.200576"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.5.1223"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-0513"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa073059"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2011.891"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2008.42"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-2972E"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-2966"},{"key":"e_1_2_8_10_1","first-page":"A398","article-title":"Micronates: 401\u2013500 grams: the NICHD Neonatal Research Network Experience 1996\u20132001","volume":"53","author":"Fanaroff AA","year":"2003","journal-title":"Pediatr. 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