{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T04:42:37Z","timestamp":1771476157458,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,12,23]],"date-time":"2013-12-23T00:00:00Z","timestamp":1387756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2014,3]]},"abstract":"Aim<\/jats:title>An estimated 140 pregnancies are diagnosed with congenital diaphragmatic hernia (CDH<\/jats:styled-content>) in Australia and N<\/jats:styled-content>ew Z<\/jats:styled-content>ealand each year, with these fetuses having a less than even chance of 1\u2010year survival. Fetoscopic endoluminal tracheal occlusion (FETO<\/jats:styled-content>) is a relatively new technique that offers a prenatal interventional strategy for selective cases of CDH<\/jats:styled-content>. This is not routinely offered in A<\/jats:styled-content>ustralia or N<\/jats:styled-content>ew Z<\/jats:styled-content>ealand. The aim of this systematic review is to critically appraise controlled clinical trials investigating the role of FETO<\/jats:styled-content> in moderate and severe isolated CDH<\/jats:styled-content> and explore whether this treatment is justified within our region.<\/jats:p><\/jats:sec>Methods<\/jats:title>A systematic literature search of multiple electronic databases was undertaken, with restrictions to human subjects and controlled clinical trials.<\/jats:p><\/jats:sec>Results<\/jats:title>Nine relevant studies were identified. No current evidence was found in favour of FETO<\/jats:styled-content> for moderate severity CDH<\/jats:styled-content>. For severe CDH<\/jats:styled-content>, the most recent evidence demonstrates significantly improved survival following FETO<\/jats:styled-content> performed using contemporary percutaneous minimally invasive techniques. Optimum timing for balloon insertion, removal and occlusion duration remains conjectural. Substantial variation in survival rates observed among control groups highlights the impact of post\u2010natal care in prenatally diagnosed CDH<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Until recently, evidence to support a role for FETO<\/jats:styled-content> in prenatal CDH<\/jats:styled-content> management was weak. Recently reported and ongoing controlled trials give cause for optimism, with improved FETO<\/jats:styled-content> safety and increased survival reported for severe CDH<\/jats:styled-content> cases. Should Australasia embrace FETO<\/jats:styled-content> for selected CDH<\/jats:styled-content> cases, a co\u2010ordinated, evidence\u2010informed service should be established under the guidance of experienced international partnerships.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12457","type":"journal-article","created":{"date-parts":[[2013,12,23]],"date-time":"2013-12-23T11:57:51Z","timestamp":1387799871000},"page":"226-233","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Fetoscopic endoluminal tracheal occlusion (FETO) for congenital diaphragmatic hernia in Australia and New Zealand: Are we willing, able, both or neither?"],"prefix":"10.1111","volume":"50","author":[{"given":"Thomas P","family":"Cundy","sequence":"first","affiliation":[{"name":"Department of Paediatric Surgery Women's and Children's Hospital Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glenn 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