{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:29:23Z","timestamp":1767832163202,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,12,23]],"date-time":"2013-12-23T00:00:00Z","timestamp":1387756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>Varicella is now a vaccine\u2010preventable disease but is generally considered benign, making it a low priority for a funded universal immunisation scheme. We aimed to increase the knowledge of the severity, morbidity and mortality caused by varicella, by a review of cases requiring paediatric intensive care in <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ew <jats:styled-content style=\"fixed-case\">Z<\/jats:styled-content>ealand where vaccine is available but not funded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective chart review of children admitted to the paediatric intensive care unit (<jats:styled-content style=\"fixed-case\">PICU<\/jats:styled-content>) over a 10\u2010year period (<jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>uly 2001\u2013<jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>uly 2011) identified from the <jats:styled-content style=\"fixed-case\">PICU<\/jats:styled-content> database with a primary or secondary code for varicella.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010four cases were identified and 26 cases were included. Of the 26 cases, 84.6% were <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>aori or <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>acific <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>sland ethnicity, 54% had no preceding medical condition and 23% were immunocompromised. Main <jats:styled-content style=\"fixed-case\">PICU<\/jats:styled-content> admission reasons were neurologic (38.5%), secondary bacterial sepsis or shock (26.9%), respiratory (15.4%), disseminated varicella (11.5%), or other causes (7.7%). Fifty per cent of children required inotropic support and 81% invasive ventilation. Four children died (15%), three of whom were immunocompromised. A further eight children (31%) had ongoing disability at hospital discharge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Varicella, or its secondary complications, requiring paediatric intensive care, carries high mortality, particularly for immunocompromised patients, and long\u2010term morbidities, mostly affecting previously healthy children.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12473","type":"journal-article","created":{"date-parts":[[2013,12,23]],"date-time":"2013-12-23T11:51:24Z","timestamp":1387799484000},"page":"280-285","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Varicella in a <scp>P<\/scp>aediatric <scp>I<\/scp>ntensive <scp>C<\/scp>are <scp>U<\/scp>nit: 10\u2010year review from <scp>S<\/scp>tarship <scp>C<\/scp>hildren's <scp>H<\/scp>ospital, <scp>N<\/scp>ew <scp>Z<\/scp>ealand"],"prefix":"10.1111","volume":"50","author":[{"given":"Sophie Chien\u2010Hui","family":"Wen","sequence":"first","affiliation":[{"name":"Department of Paediatric Infectious Disease Starship Children's Hospital  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona","family":"Miles","sequence":"additional","affiliation":[{"name":"Department of Paediatric Intensive Care Unit Starship Children's Hospital  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brent","family":"McSharry","sequence":"additional","affiliation":[{"name":"Department of Paediatric Intensive Care Unit Starship Children's Hospital  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Wilson","sequence":"additional","affiliation":[{"name":"Department of Paediatric Infectious Disease Starship Children's Hospital  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,12,23]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"783","volume-title":"Vaccines","author":"Gershon AA","year":"2004"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(05)70313-5"},{"key":"e_1_2_9_4_1","first-page":"319","volume-title":"Immunisation Handbook 2011","author":"Ministry of Health","year":"2011"},{"key":"e_1_2_9_5_1","unstructured":"Statistics New Zealand [Internet].Census data \u2013 quick facts about New Zealand's population and dwellings 2006. 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