{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:00:07Z","timestamp":1792623607203,"version":"4.5.0"},"reference-count":69,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T00:00:00Z","timestamp":1392595200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>Congenital diaphragmatic hernia is an uncommon congenital anomaly of the diaphragm with pulmonary hypoplasia and persistent pulmonary hypertension as serious consequences. Despite recent advances in therapy, congenital diaphragmatic hernia remains a challenging condition. Best treatment strategies are still largely unknown, and practice strategies vary widely among different centres. Additionally, as congenital diaphragmatic hernia is a relatively uncommon condition, it is difficult to recruit sufficient numbers of patients for clinical trials. In recent years, survival rates of congenital diaphragmatic hernia patients appear to have increased. With the progressively improved survival rates, the long\u2010term prognosis and quality of life of patients have become an increasingly important issue. Survivors have been shown to be at risk for many long\u2010term morbidities, which highlights the importance of long\u2010term follow\u2010up of these children. The aim of this review is to give an overview of the current knowledge regarding congenital diaphragmatic hernia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12508","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T12:13:11Z","timestamp":1392639191000},"page":"667-673","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":109,"title":["Congenital diaphragmatic hernia"],"prefix":"10.1111","volume":"50","author":[{"given":"Lisette","family":"Leeuwen","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine The Children's Hospital at Westmead  Sydney New South Wales Australia"},{"name":"Medical School University of Groningen  Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominic A","family":"Fitzgerald","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine The Children's Hospital at Westmead  Sydney New South Wales Australia"},{"name":"Discipline of Paediatrics and Child Health Sydney Medical School University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,2,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0095-5108(18)30201-X"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800580507"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)80162-0"},{"key":"e_1_2_10_5_1","volume-title":"The Developing Human: Clinically Oriented Embryology","author":"Moore KL","year":"2008"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22553"},{"key":"e_1_2_10_7_1","first-page":"L362","article-title":"Nitrofen dose\u2010dependent gestational day\u2010specific murine lung hypoplasia and left\u2010sided diaphragmatic hernia","volume":"272","author":"Cilley RE","year":"1997","journal-title":"Am. J. Physiol."},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1997.83.2.338"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65000-6"},{"key":"e_1_2_10_10_1","first-page":"888","article-title":"Incidence of congenital diaphragmatic hernia in the young of rats bred on a diet deficient in vitamin A","volume":"62","author":"Andersen DH","year":"1941","journal-title":"Am. J. Dis. Child."},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1000920202"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1203\/01.PDR.0000062660.12769.E6"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003830050399"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-0521"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20716"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2009.00247.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2009.188"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.2008.01031.x"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19980923)79:3<215::AID-AJMG13>3.0.CO;2-K"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1086\/513442"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.30131"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2002.00635.x"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2005.04.002"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2009.07.012"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-009-2425-8"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-008-0917-7"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-002-0743-1"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.30127"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6450"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.10142"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa035005"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2011.03.050"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(95)90042-X"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2007.01.006"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2009.07.025"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001340051284"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2001-12204"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003830050398"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2012.05.046"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001340.pub2"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)04100-1"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(99)90363-9"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.110.3.590"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2003.11.031"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e3182231872"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2012.12.009"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2003.11.010"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.12.036"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.99.6.838"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1159\/000097125"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/jpsu.2003.50194"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2010.09.060"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-2845"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2009.01.046"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(78)80391-1"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-3282"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-8-89"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1950110109"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2006.05.044"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22557"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2006.01.026"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(09)90013-0"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2004.09.037"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2001.25746"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(02)04278-9"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.01.042"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200205000-00022"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0095-5108(18)30214-8"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(96)90494-7"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-008-2257-y"}],"container-title":["Journal of Paediatrics and Child Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjpc.12508","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjpc.12508","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jpc.12508","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T10:51:36Z","timestamp":1696243896000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jpc.12508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,17]]},"references-count":69,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["10.1111\/jpc.12508"],"URL":"https:\/\/doi.org\/10.1111\/jpc.12508","archive":["Portico"],"relation":{},"ISSN":["1034-4810","1440-1754"],"issn-type":[{"value":"1034-4810","type":"print"},{"value":"1440-1754","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,17]]},"assertion":[{"value":"2014-01-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-02-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}