{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T06:32:22Z","timestamp":1777962742146,"version":"3.51.4"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,11,20]],"date-time":"2014-11-20T00:00:00Z","timestamp":1416441600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["572742"],"award-info":[{"award-number":["572742"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Foundation for Alcohol Research and Education","award":["1832\/2442"],"award-info":[{"award-number":["1832\/2442"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>There is increasing attention on fetal alcohol spectrum disorders (<jats:styled-content style=\"fixed-case\">FASD<\/jats:styled-content>) in Australia, but there are limited data on their birth prevalence. Our aim was to report on the birth prevalence of <jats:styled-content style=\"fixed-case\">FASD<\/jats:styled-content> in Western Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data on notified cases of <jats:styled-content style=\"fixed-case\">FASD<\/jats:styled-content> born in <jats:styled-content style=\"fixed-case\">Western Australia<\/jats:styled-content> 1980\u20132010 were identified from the <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>estern <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralian <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>egister of <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>evelopmental <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>nomalies. Tabulated denominator data were obtained from the <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>idwives <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>otification <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ystem. Prevalence rates per 1000 births were calculated by demographic variables. Prevalence ratios (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>s) and 95% confidence intervals (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>s) of Aboriginal compared with non\u2010Aboriginal prevalence rates were calculated. <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>s were also calculated to compare rates for births 2000\u20132010 with 1980\u20131989.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred ten cases of <jats:styled-content style=\"fixed-case\">FASD<\/jats:styled-content>s were identified: a birth prevalence of 0.26\/1000 births (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.23\u20130.30). The majority of cases reported were <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal (89.5%), a rate of 4.08\/1000, compared with 0.03\/1000 in notified non\u2010<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal cases, giving a <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> of 139 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 89\u2013215). The prevalence of <jats:styled-content style=\"fixed-case\">FASD<\/jats:styled-content> in 2000\u20132010 was over twice that in 1980\u20131989 for both <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> 2.37; <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.60\u20133.51) and non\u2010<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> 2.13; <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.68\u20136.69) children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There has been a twofold increase in <jats:styled-content style=\"fixed-case\">FASD<\/jats:styled-content> notifications in <jats:styled-content style=\"fixed-case\">Western Australia<\/jats:styled-content> over the last 30 years. Population surveillance data such as these are valuable in advocating for and monitoring the effectiveness of preventive activities and diagnostic and management services.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12746","type":"journal-article","created":{"date-parts":[[2014,11,21]],"date-time":"2014-11-21T02:35:43Z","timestamp":1416537343000},"page":"433-436","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Fetal alcohol spectrum disorders: Notifications to the <scp>W<\/scp>estern <scp>A<\/scp>ustralian <scp>R<\/scp>egister of <scp>D<\/scp>evelopmental <scp>A<\/scp>nomalies"],"prefix":"10.1111","volume":"51","author":[{"given":"Raewyn C","family":"Mutch","sequence":"first","affiliation":[{"name":"Paediatric and Adolescent Medicine\/Refugee Health Princess Margaret Hospital for Children  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rochelle","family":"Watkins","sequence":"additional","affiliation":[{"name":"Telethon Kids Institute University of Western Australia  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carol","family":"Bower","sequence":"additional","affiliation":[{"name":"Western Australian Register of Developmental Anomalies King Edward Memorial Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,11,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/dar.12047"},{"key":"e_1_2_8_3_1","unstructured":"BowerC RudyE CallaghanA CosgroveP QuickJReport of the Birth Defects Registry of Western Australia 1980\u20132006. 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