{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T15:55:43Z","timestamp":1775836543441,"version":"3.50.1"},"reference-count":52,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,10,15]],"date-time":"2014-10-15T00:00:00Z","timestamp":1413331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Bacteraemias in children are an important cause of morbidity and mortality. Knowledge of local epidemiology and trends is important to inform practitioners of likely pathogens in the sick child. This study aimed to determine trends over time in pathogenic organisms causing paediatric bacteraemia in <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>orth <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>ueensland and to audit a hospital's blood culture results with respect to contamination rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective review of 8385 blood cultures collected from children attending a tertiary centre in <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>orth <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>ueensland over a 10\u2010year period (2001\u20132010).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 696 positive blood cultures (8.3%) with 70 different bacterial species detected. <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>ram\u2010positive and <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>ram\u2010negative bacteria accounted for 48.6% and 51.4% of isolates, respectively. Overall, bacteraemia accounted for 4.7 per 1000 admissions. The rate of contamination was 60.6% among positive blood cultures and 5.0% for all blood cultures sampled. These results were compared with previous published reports. Notable differences were seen in the frequencies of <jats:styled-content style=\"fixed-case\"><jats:italic>S<\/jats:italic><\/jats:styled-content><jats:italic>almonella<\/jats:italic> and group A <jats:styled-content style=\"fixed-case\"><jats:italic>S<\/jats:italic><\/jats:styled-content><jats:italic>treptococcus<\/jats:italic> bacteraemias in <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>orth <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>ueensland when compared with other reports. There was also a decline in vaccine\u2010preventable infections such as <jats:styled-content style=\"fixed-case\"><jats:italic>S<\/jats:italic><\/jats:styled-content><jats:italic>.\u2009pneumoniae<\/jats:italic> and an increasing trend of community\u2010acquired <jats:styled-content style=\"fixed-case\">MRSA<\/jats:styled-content> bacteraemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study has demonstrated the unique profile of causative pathogens of paediatric bacteraemias in tropical <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia. In light of the increasing prevalence of <jats:styled-content style=\"fixed-case\">MRSA<\/jats:styled-content>, empiric treatment for sepsis for children in this region needs to be reconsidered.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12750","type":"journal-article","created":{"date-parts":[[2014,10,15]],"date-time":"2014-10-15T09:39:51Z","timestamp":1413365991000},"page":"437-442","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Paediatric bacteraemias in tropical <scp>A<\/scp>ustralia"],"prefix":"10.1111","volume":"51","author":[{"given":"Jeremy","family":"Er","sequence":"first","affiliation":[{"name":"Townsville Hospital  Townsville Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Wallis","sequence":"additional","affiliation":[{"name":"Townsville Hospital  Townsville Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Maloney","sequence":"additional","affiliation":[{"name":"Townsville Hospital  Townsville Queensland Australia"},{"name":"Pathology Queensland  Townsville Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Norton","sequence":"additional","affiliation":[{"name":"Townsville Hospital  Townsville Queensland Australia"},{"name":"Pathology Queensland  Townsville Queensland Australia"},{"name":"School of Medicine and Dentistry James Cook University  Townsville Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1990.tb136941.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2009.10.012"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e318187ad5a"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.015271-0"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2010.01841.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.05503-0"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000088115"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70072-4"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa040275"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e318187a87d"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.1997.tb01666.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2004.01269.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1987.tb133640.x"},{"key":"e_1_2_7_15_1","first-page":"441","article-title":"Invasive pneumococcal disease in Australia, 2003","volume":"28","author":"Roche P","year":"2004","journal-title":"Commun. 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