{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T19:45:43Z","timestamp":1789069543364,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,11,19]],"date-time":"2014-11-19T00:00:00Z","timestamp":1416355200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001515","name":"Cure Kids","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001515","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2015,6]]},"abstract":"Aim<\/jats:title>This study aims to report the aetiology and outcome of dilated cardiomyopathy (DCM<\/jats:styled-content>) in children from N<\/jats:styled-content>ew Z<\/jats:styled-content>ealand and to assess the outcome of protocolised family cardiac investigation introduced in 2007.<\/jats:p><\/jats:sec>Methods<\/jats:title>Retrospective review of all patients with DCM<\/jats:styled-content>, aged <15 years, presenting to the children's hospital between 01\/01\/2007 and 01\/03\/2012. Oncology patients were excluded. Family screening results were assessed.<\/jats:p><\/jats:sec>Results<\/jats:title>Thirty\u2010five patients were identified. Median age 1 year: 26\/35 (74%) <5 years. Ethnicity: N<\/jats:styled-content>ew Z<\/jats:styled-content>ealand E<\/jats:styled-content>uropean 14\/35 (40%), M<\/jats:styled-content>aori 11\/35 (31%), P<\/jats:styled-content>acific Island 5\/35 (14%) and other 5\/35(14%). Excluding the four cases with biopsy\u2010proven myocarditis, family cardiac screening was documented in 15\/31 (48%). Of these, 7\/15 (47%) had a positive family screen. Six previously undiagnosed DCM<\/jats:styled-content> cases were found in these families. Five of the seven familial DCM<\/jats:styled-content> cases had evidence of viral infection at presentation. Final aetiology: Myocarditis<\/jats:italic>, 15\/35 (43%), with P<\/jats:styled-content>arvovirus being the commonest virus identified 10\/15(67%). Familial<\/jats:italic>, seven (20%), Idiopathic<\/jats:italic>, seven (20%), Others<\/jats:italic>, six (17%). Overall outcome was death 10\/35(28%), ongoing dysfunction 16\/35 (46%) and normalisation in 9\/35 (26%). The median time to death from diagnosis was 1.5 months (3 days to 3 years). Death occurred in 4\/7 with familial DCM<\/jats:styled-content> (57%) compared with 6\/28 (21%) among the others (ns). Recovery occurred in 0\/7 with familial DCM<\/jats:styled-content> versus 4\/4 with biopsy proven myocarditis (P<\/jats:italic> < 0.05).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Almost half of families screened had evidence of familial DCM<\/jats:styled-content>, and these children carried a worse prognosis. M<\/jats:styled-content>aori and P<\/jats:styled-content>acific Island children seem to be over\u2010represented. Family investigation led to the identification of many pre\u2010symptomatic individuals even when viral aetiology was suspected initially.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12787","type":"journal-article","created":{"date-parts":[[2014,11,20]],"date-time":"2014-11-20T06:22:51Z","timestamp":1416464571000},"page":"595-599","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Dilated cardiomyopathy in children: Review of all presentations to a children's hospital over a 5\u2010year period and the impact of family cardiac screening"],"prefix":"10.1111","volume":"51","author":[{"given":"Verangi CK","family":"Herath","sequence":"first","affiliation":[{"name":"Green Lane Paediatric and Congenital Cardiac Services Starship Children's Hospital Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas L","family":"Gentles","sequence":"additional","affiliation":[{"name":"Green Lane Paediatric and Congenital Cardiac Services Starship Children's Hospital Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan R","family":"Skinner","sequence":"additional","affiliation":[{"name":"Green Lane Paediatric and Congenital Cardiac Services Starship Children's Hospital Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0b013e3283462257"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.174287"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.635128"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hfc.2010.05.002"},{"key":"e_1_2_9_6_1","unstructured":"Statistics New Zealand.2006 Census Data Wellington: Statistics New Zealand 2006. 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