{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T10:33:33Z","timestamp":1794047613651,"version":"4.8.0"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,1,15]],"date-time":"2015-01-15T00:00:00Z","timestamp":1421280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Health and Medical Research Council of Australia","award":["1024474"],"award-info":[{"award-number":["1024474"]}]},{"DOI":"10.13039\/501100001027","name":"Australian Government Department of Health and Ageing","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001027","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Australian Government Department of Families, Housing, Community Services and Indigenous Affairs"},{"name":"Save the Children Australia"},{"DOI":"10.13039\/501100015794","name":"Foundation for Alcohol Research and Education","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100015794","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National Health and Medical Research Council of Australia Practitioner Fellowships","award":["457084"],"award-info":[{"award-number":["457084"]}]},{"name":"National Health and Medical Research Council of Australia Practitioner Fellowships","award":["1021480"],"award-info":[{"award-number":["1021480"]}]},{"name":"Australian Research Council Future Fellowship","award":["0130007"],"award-info":[{"award-number":["0130007"]}]},{"name":"McCusker Clinical Research Fellowship"},{"name":"National Health and Medical Research Council Research Fellowship","award":["634341"],"award-info":[{"award-number":["634341"]}]},{"name":"Poche Centre for Indigenous Health Fellowship"},{"name":"Sydney School of Public Health"},{"DOI":"10.13039\/501100001774","name":"University of Sydney","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001774","id-type":"DOI","asserted-by":"crossref"}]},{"name":"an Australian Postgraduate Award"},{"name":"a Curtin University Postgraduate Scholarship"},{"name":"Faculty Postgraduate Award"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2015,4]]},"abstract":"Aim<\/jats:title>Aboriginal leaders concerned about high rates of alcohol use in pregnancy invited researchers to determine the prevalence of fetal alcohol syndrome (FAS<\/jats:styled-content>) and partial fetal alcohol syndrome (pFAS<\/jats:styled-content>) in their communities.<\/jats:p><\/jats:sec>Methods<\/jats:title>Population\u2010based prevalence study using active case ascertainment in children born in 2002\/2003 and living in the F<\/jats:styled-content>itzroy V<\/jats:styled-content>alley, in W<\/jats:styled-content>estern A<\/jats:styled-content>ustralia (A<\/jats:styled-content>pril 2010\u2013N<\/jats:styled-content>ovember 2011) (n =<\/jats:italic> 134). Socio\u2010demographic and antenatal data, including alcohol use in pregnancy, were collected by interview with 127\/134 (95%) consenting parents\/care givers. Maternal\/child medical records were reviewed. Interdisciplinary assessments were conducted for 108\/134 (81%) children. FAS\/pFAS<\/jats:styled-content> prevalence was determined using modified C<\/jats:styled-content>anadian diagnostic guidelines.<\/jats:p><\/jats:sec>Results<\/jats:title>In 127 pregnancies, alcohol was used in 55%. FAS<\/jats:styled-content> or pFAS<\/jats:styled-content> was diagnosed in 13\/108 children, a prevalence of 120 per 1000 (95% confidence interval 70\u2013196). Prenatal alcohol exposure was confirmed for all children with FAS\/pFAS<\/jats:styled-content>, 80% in the first trimester and 50% throughout pregnancy. Ten of 13 mothers had Alcohol Use Disorders Identification Test scores and all drank at a high\u2010risk level. Of children with FAS\/pFAS<\/jats:styled-content>, 69% had microcephaly, 85% had weight deficiency and all had facial dysmorphology and central nervous system abnormality\/impairment in three to eight domains.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The population prevalence of FAS\/pFAS<\/jats:styled-content> in remote A<\/jats:styled-content>boriginal communities of the F<\/jats:styled-content>itzroy V<\/jats:styled-content>alley is the highest reported in A<\/jats:styled-content>ustralia and similar to that reported in high\u2010risk populations internationally. Results are likely to be generalisable to other age groups in the F<\/jats:styled-content>itzroy V<\/jats:styled-content>alley and other remote A<\/jats:styled-content>ustralian communities with high\u2010risk alcohol use during pregnancy. Prevention of FAS\/pFAS<\/jats:styled-content> is an urgent public health challenge.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12814","type":"journal-article","created":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T07:48:46Z","timestamp":1599724126000},"page":"450-457","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":76,"title":["Prevalence of fetal alcohol syndrome in a population\u2010based sample of children living in remote A<\/scp>ustralia: The L<\/scp>ililwan Project"],"prefix":"10.1111","volume":"51","author":[{"given":"James P","family":"Fitzpatrick","sequence":"first","affiliation":[{"name":"Discipline of Paediatrics and Child Health Sydney Medical School University of Sydney Sydney Australia"},{"name":"Musculoskeletal Division, The George Institute for Global Health Sydney Medical School University of Sydney Sydney Australia"},{"name":"Poche Centre for Indigenous Health Sydney Medical School University of 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Health Sydney Medical School University of Sydney Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Carmichael Olson","sequence":"additional","affiliation":[{"name":"Population Sciences Division, Telethon Kids Institute The University of Western Australia Perth Australia"},{"name":"School of Public Health Curtin University Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara R","family":"Lucas","sequence":"additional","affiliation":[{"name":"Discipline of Paediatrics and Child Health Sydney Medical School University of Sydney Sydney Australia"},{"name":"Musculoskeletal Division, The George Institute for Global Health Sydney Medical School University of Sydney Sydney Australia"},{"name":"Nindilingarri Cultural Health Services Fitzroy Crossing Australia"},{"name":"Marninwarntikura Fitzroy Women's Resource Centre Fitzroy Crossing 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Sydney Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marmingee","family":"Hand","sequence":"additional","affiliation":[{"name":"Derby Allied Health Service Western Australian Country Health Services Derby Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rochelle E","family":"Watkins","sequence":"additional","affiliation":[{"name":"Poche Centre for Indigenous Health Sydney Medical School University of Sydney Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra LC","family":"Martiniuk","sequence":"additional","affiliation":[{"name":"Musculoskeletal Division, The George Institute for Global Health Sydney Medical School University of Sydney Sydney Australia"},{"name":"Department of Education and Early Childhood Development Government of Victoria Newcastle Washington USA"},{"name":"Faculty of Health The University of Newcastle Newcastle Washington 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