{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T10:38:57Z","timestamp":1766486337081},"reference-count":33,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,6,3]],"date-time":"2015-06-03T00:00:00Z","timestamp":1433289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Australian National Health and Medical Research Council","award":["491246"],"award-info":[{"award-number":["491246"]}]},{"name":"Centre of Clinical Research Excellence","award":["546519"],"award-info":[{"award-number":["546519"]}]},{"name":"Early Career Fellowship","award":["1053787","1012236"],"award-info":[{"award-number":["1053787","1012236"]}]},{"name":"Victorian Government Operational Infrastructure Support Program"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2015,11]]},"abstract":"Aim<\/jats:title>Extremely preterm (EPT<\/jats:styled-content>, born <28 weeks gestation) or extremely low birthweight (ELBW<\/jats:styled-content>, birthweight <1000\u2009g) individuals are at increased risk of high blood pressure (BP<\/jats:styled-content>) and cardiovascular disease. We compared office BP<\/jats:styled-content> measurements with 24\u2010h ambulatory BP<\/jats:styled-content> measurement (ABP<\/jats:styled-content>) in EPT<\/jats:styled-content>\/ELBW<\/jats:styled-content> individuals at age 18 years and term controls, and determined the sensitivity and specificity of office BP<\/jats:styled-content> in predicting masked hypertension (24\u2010h ABP<\/jats:styled-content> measurements\u2009>\u2009130\/80).<\/jats:p><\/jats:sec>Methods<\/jats:title>All EPT<\/jats:styled-content>\/ELBW<\/jats:styled-content> individuals and matched term control adolescents born in V<\/jats:styled-content>ictoria, A<\/jats:styled-content>ustralia, between 1991 and 1992 were recruited. A subset of this cohort was seen at 18 years, and researchers blinded to birth status measured office BP<\/jats:styled-content> and ABP<\/jats:styled-content>. We established the office BP<\/jats:styled-content> thresholds that had the highest sensitivity and specificity in predicting masked hypertension.<\/jats:p><\/jats:sec>Results<\/jats:title>EPT<\/jats:styled-content>\/ELBW<\/jats:styled-content> (N =<\/jats:italic> 120) individuals had higher mean BP<\/jats:styled-content> measurements at 18 years, compared with controls (N =<\/jats:italic> 71). Although there were no significant differences in rates of high BP<\/jats:styled-content> between groups, high proportions of both EPT<\/jats:styled-content>\/ELBW<\/jats:styled-content> (43.3%) and term control (36.6%) participants met criteria for masked systolic hypertension. In EPT<\/jats:styled-content>\/ELBW<\/jats:styled-content> individuals, office systolic BP<\/jats:styled-content> measurement of \u2265122.5\u2009mmHg predicted masked systolic hypertension (sensitivity 79%, specificity 74%). Office diastolic BP<\/jats:styled-content> measurement of \u226575.5\u2009mmHg predicted masked diastolic hypertension (sensitivity 77%, specificity, 77%).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>At age 18 years, EPT<\/jats:styled-content>\/ELBW<\/jats:styled-content> individuals have higher systolic and diastolic BP<\/jats:styled-content>, compared with controls. Office BP<\/jats:styled-content> may be an adequate screen for masked hypertension in EPT<\/jats:styled-content>\/ELBW<\/jats:styled-content> survivors, but further research is needed to identify accurate ABP<\/jats:styled-content> thresholds for masked hypertension for young Australians.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12928","type":"journal-article","created":{"date-parts":[[2015,6,3]],"date-time":"2015-06-03T22:09:25Z","timestamp":1433369365000},"page":"1060-1065","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Masked hypertension in extremely preterm adolescents"],"prefix":"10.1111","volume":"51","author":[{"given":"Johanna C","family":"Centra","sequence":"first","affiliation":[{"name":"Department of Paediatrics Barwon Health Geelong Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gehan","family":"Roberts","sequence":"additional","affiliation":[{"name":"Royal Children's Hospital Melbourne Victoria Australia"},{"name":"Murdoch Children's Research Institute Melbourne Victoria Australia"},{"name":"University of Melbourne Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gillian","family":"Opie","sequence":"additional","affiliation":[{"name":"Mercy Hospital for Women Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeanie","family":"Cheong","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute Melbourne Victoria Australia"},{"name":"University of Melbourne Melbourne Victoria Australia"},{"name":"Royal Women's Hospital Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lex W","family":"Doyle","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute Melbourne Victoria Australia"},{"name":"University of Melbourne Melbourne Victoria Australia"},{"name":"Royal Women's Hospital Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Victorian Infant Collaborative Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,6,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/31.6.1235"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02384-9"},{"issue":"1","key":"e_1_2_9_4_1","first-page":"2","article-title":"Insulin sensitivity in people born pre\u2010term, with low or very low birth weight and small for gestational age","volume":"29","author":"Hofman PL","year":"2006","journal-title":"J. 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