{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T04:40:23Z","timestamp":1767847223092,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,6,3]],"date-time":"2015-06-03T00:00:00Z","timestamp":1433289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NZ Ministry of Health"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Varicella is a vaccine\u2010preventable disease not notifiable in <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ew <jats:styled-content style=\"fixed-case\">Z<\/jats:styled-content>ealand (<jats:styled-content style=\"fixed-case\">NZ<\/jats:styled-content>), and varicella vaccine is not funded in the <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ational <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>mmunisation <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>chedule (<jats:styled-content style=\"fixed-case\">NIS<\/jats:styled-content>). Hospitalisations can occur because of bacterial secondary infection and other complications, which can result in long\u2010term sequelae. Varicella may not be acknowledged in discharge coding when complications occur weeks after infection. Using the New Zealand Paediatric Surveillance Unit (NZPSU), the aim of this study was to document the hospitalisation burden of this disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cases (0\u201314years) of varicella and post\u2010varicella complications requiring hospitalisation, including stroke syndromes where varicella occurred in the preceding 6 months, were notified to <jats:styled-content style=\"fixed-case\">NZPSU<\/jats:styled-content> between 1 November 2011 and 31 October 2013. Herpes zoster cases were excluded. Questionnaires were used to capture demographics, clinical features, management and short\u2010term outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred seventy\u2010eight notifications were received and 144 were confirmed cases. Overall incidence was 8.3\/100\u2009000 children per year. Fifty\u2010two\u2009per\u2009cent were women with a median age of 2.4 years. <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>\u0101ori and <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>acific <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>sland (<jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content>) children accounted for 74% of hospitalisations, with incidence rate ratios compared with <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>uropean children of 2.8 and 3.9, respectively (<jats:italic>P<\/jats:italic> &lt; 0.01). Complications included: infection (75%), respiratory (11%), neurological (11%), electrolyte disturbance (6%) and haemorrhagic varicella (4%). Nine\u2009per\u2009cent were immunocompromised. Median duration of hospital admission was 4 days with 9% requiring intensive care admission. There were no reported deaths; however, 19% had ongoing problems at discharge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Varicella has more associated morbidity than commonly perceived in immunocompetent children. <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>\u0101ori and <jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content> children are more likely to have complications. This surveillance gives support for inclusion of universal varicella vaccine in the <jats:styled-content style=\"fixed-case\">NZ NIS<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.12937","type":"journal-article","created":{"date-parts":[[2015,6,4]],"date-time":"2015-06-04T02:10:10Z","timestamp":1433383810000},"page":"1078-1083","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Prospective surveillance of hospitalisations associated with varicella in <scp>N<\/scp>ew <scp>Z<\/scp>ealand children"],"prefix":"10.1111","volume":"51","author":[{"given":"Sophie Chien\u2010Hui","family":"Wen","sequence":"first","affiliation":[{"name":"Departments of Paediatric Infectious Diseases Starship Children's Hospital  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emma","family":"Best","sequence":"additional","affiliation":[{"name":"Departments of Paediatric Infectious Diseases Starship Children's Hospital  Auckland New Zealand"},{"name":"Department of Paediatrics University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony","family":"Walls","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Otago  Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nigel","family":"Dickson","sequence":"additional","affiliation":[{"name":"New Zealand Paediatric Surveillance Unit Department of Women's and Children Health University of Otago  Dunedin New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamish","family":"McCay","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Auckland  Auckland New Zealand"},{"name":"Department of Paediatrics Waikato Hospital  Waikato Hamilton New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Wilson","sequence":"additional","affiliation":[{"name":"Departments of Paediatric Infectious Diseases Starship Children's Hospital  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,6,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2007.123232"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-005-1637-8"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.12473"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-3385"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31827e92b7"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(05)70313-5"},{"key":"e_1_2_9_8_1","unstructured":"Statistics New Zealand.Census regional summary tables \u2013 parts 1 and 2.2013. 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