{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T19:52:08Z","timestamp":1785873128602,"version":"3.56.0"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,3]],"date-time":"2016-05-03T00:00:00Z","timestamp":1462233600000},"content-version":"vor","delay-in-days":32,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003842","name":"Ilhan Food Allergy Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003842","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine whether infant\u2010feeding practices, including duration of exclusive breastfeeding and use of partially hydrolysed formula, modify the risk of developing infant food allergy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In an observational population\u2010based study, 1\u2009year olds were recruited from community immunisation clinics in Melbourne, Australia. Parent\u2010reported data on infant\u2010feeding practices and potential confounders were collected prior to infant skin prick testing for four food allergens. Sensitised infants attended hospital\u2010based oral food challenges to establish food allergy status. Multiple logistic regression was used to investigate associations between breastfeeding and formula\u2010feeding and infant food allergy adjusting for possible confounding variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 5276 (74% response) infants participated. Of the 4537 for whom food allergy status was determined, 515 (11.3%) were food allergic (challenge\u2010proven in the context of skin prick testing positive (\u22652\u2009mm)). After adjusting for confounding variables, there was no association between duration of exclusive breastfeeding and food allergy. Use of partially hydrolysed formula did not reduce the risk of food allergy compared with cow's milk formula in the general population (adjusted odds ratios 1.03 (confidence interval 0.67\u20131.50)).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Duration of exclusive breastfeeding and use of partially hydrolysed formula were not associated with food allergy at 1\u2009year of age in this large population\u2010based study. These findings have implications for population\u2010based infant\u2010feeding guidelines and do not support the use of partially hydrolysed formula for food allergy prevention.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.13109","type":"journal-article","created":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T16:02:55Z","timestamp":1462377775000},"page":"377-384","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Formula and breast feeding in infant food allergy: A population\u2010based study"],"prefix":"10.1111","volume":"52","author":[{"given":"Alice J","family":"Goldsmith","sequence":"first","affiliation":[{"name":"School of Medicine, Sydney University of Notre Dame  Sydney New South Wales Australia"},{"name":"Murdoch Childrens Research Institute  Parkville Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer J","family":"Koplin","sequence":"additional","affiliation":[{"name":"Murdoch Childrens Research Institute  Parkville Australia"},{"name":"Department of Paediatrics The University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian J","family":"Lowe","sequence":"additional","affiliation":[{"name":"Murdoch Childrens Research Institute  Parkville Australia"},{"name":"The Centre for Environmental, Genetic and Analytic Epidemiology University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mimi LK","family":"Tang","sequence":"additional","affiliation":[{"name":"Murdoch Childrens Research Institute  Parkville Australia"},{"name":"Department of Allergy and Immunology The Royal Children's Hospital  Melbourne Australia"},{"name":"Department of Paediatrics The University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie C","family":"Matheson","sequence":"additional","affiliation":[{"name":"The Centre for Environmental, Genetic and Analytic Epidemiology University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marnie","family":"Robinson","sequence":"additional","affiliation":[{"name":"Department of Allergy and Immunology The Royal Children's Hospital  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Peters","sequence":"additional","affiliation":[{"name":"Murdoch Childrens Research Institute  Parkville Australia"},{"name":"Department of Paediatrics The University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyamali C","family":"Dharmage","sequence":"additional","affiliation":[{"name":"Murdoch Childrens Research Institute  Parkville Australia"},{"name":"The Centre for Environmental, Genetic and Analytic Epidemiology University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrina J","family":"Allen","sequence":"additional","affiliation":[{"name":"Murdoch Childrens Research Institute  Parkville Australia"},{"name":"Department of Allergy and Immunology The Royal Children's Hospital  Melbourne Australia"},{"name":"Department of Paediatrics The University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69283-0"},{"key":"e_1_2_8_3_1","unstructured":"Australasian Society of Clinical Immunology and Allergy (ASCIA).The Economic Impact of Allergic Disease in Australia: Not to be Sneezed at. 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