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Non\u2010inflammatory joint stiffness or pain, carpal tunnel syndrome, trigger fingers, unexplained pain crises and short stature should all prompt consideration of a lysosomal storage disorder. Recurrent ENT infections, hepatosplenomegaly, recurrent hernias and visual\/hearing impairment \u2013 especially when clustered together \u2013 are important extra\u2010skeletal features. As diagnostic and therapeutic options continue to evolve, children with lysosomal storage disorders and their families are facing more sophisticated options for screening and treatment. The aim of this article is to highlight the paediatric presentations of lysosomal storage disorders, with an emphasis on the musculoskeletal features.<\/jats:p>","DOI":"10.1111\/jpc.13122","type":"journal-article","created":{"date-parts":[[2016,4,30]],"date-time":"2016-04-30T00:41:46Z","timestamp":1461976906000},"page":"262-271","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Lysosomal storage disorders: A review of the musculoskeletal features"],"prefix":"10.1111","volume":"52","author":[{"given":"Rebecca A.","family":"James","sequence":"first","affiliation":[{"name":"Department of Rheumatology Royal Children's Hospital  Melbourne Victoria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davinder","family":"Singh\u2010Grewal","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Children's Hospital at Westmead  Sydney New South Wales"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Senq\u2010J","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Princess Margaret Hospital  Perth Western Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim","family":"McGill","sequence":"additional","affiliation":[{"name":"Department of Metabolic Medicine Lady Cilento Children's Hospital  South Brisbane"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Navid","family":"Adib","sequence":"additional","affiliation":[{"name":"Queensland Paediatric Rheumatology Services, Wesley Hospital  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the Australian Paediatric Rheumatology Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,28]]},"reference":[{"key":"e_1_2_18_2_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1012463605992"},{"key":"e_1_2_18_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.3.249"},{"key":"e_1_2_18_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2013.03.004"},{"key":"e_1_2_18_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.38.11.750"},{"key":"e_1_2_18_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.102.6.e63"},{"key":"e_1_2_18_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2005.tb02004.x"},{"key":"e_1_2_18_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/GIM.0b013e318211a7e1"},{"key":"e_1_2_18_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.095315"},{"key":"e_1_2_18_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-9-32"},{"key":"e_1_2_18_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0712(01)00010-5"},{"key":"e_1_2_18_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/BPB.0b013e328016830b"},{"key":"e_1_2_18_13_1","first-page":"387","article-title":"Carpal tunnel syndrome in children","volume":"69","author":"Van Meir N","year":"2003","journal-title":"Acta Orthop. 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