{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T07:59:04Z","timestamp":1759564744465},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,4,18]],"date-time":"2016-04-18T00:00:00Z","timestamp":1460937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HD072848\u201001A1"],"award-info":[{"award-number":["R01HD072848\u201001A1"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002428","name":"Austrian Science Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002428","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Pneumothorax is a common emergency affecting extremely preterm. In adult studies, lung ultrasound has performed better than chest x\u2010ray in the diagnosis of pneumothorax. The purpose of this study was to determine the efficacy of lung ultrasound (LUS) examination to detect pneumothorax using a preterm animal model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a prospective, observational study using newborn Border\u2013Leicester lambs at gestational age\u2009=\u2009126\u2009days (equivalent to gestational age\u2009=\u200926\u2009weeks in humans) receiving mechanical ventilation from birth to 2\u2009h of life. At the conclusion of the experiment, LUS was performed, the lambs were then euthanised and a post\u2010mortem exam was immediately performed. We used previously published ultrasound techniques to identify pneumothorax. Test characteristics of LUS to detect pneumothorax were calculated, using the post\u2010mortem exam as the \u2018gold standard\u2019 test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nine lambs (18 lungs) were examined. Four lambs had a unilateral pneumothorax, all of which were identified by LUS with no false positives.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This was the first study to use post\u2010mortem findings to test the efficacy of LUS to detect pneumothorax in a newborn animal model. Lung ultrasound accurately detected pneumothorax, verified by post\u2010mortem exam, in premature, newborn lambs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.13154","type":"journal-article","created":{"date-parts":[[2016,4,18]],"date-time":"2016-04-18T21:12:51Z","timestamp":1461013971000},"page":"643-648","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Lung ultrasound accurately detects pneumothorax in a preterm newborn lamb model"],"prefix":"10.1111","volume":"52","author":[{"given":"Douglas A","family":"Blank","sequence":"first","affiliation":[{"name":"Newborn Research Centre The Royal Women's Hospital  Melbourne Victoria Australia"},{"name":"The Hudson Institute of Medical Research Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart B","family":"Hooper","sequence":"additional","affiliation":[{"name":"The Hudson Institute of Medical Research Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corinna","family":"Binder\u2010Heschl","sequence":"additional","affiliation":[{"name":"The Hudson Institute of Medical Research Monash University  Melbourne Victoria Australia"},{"name":"Department of Neonatology Medical University of Graz  Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Kluckow","sequence":"additional","affiliation":[{"name":"Department of Neonatology Royal North Shore Hospital and University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew W","family":"Gill","sequence":"additional","affiliation":[{"name":"Centre for Neonatal Research and Education University of Western Australia  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenic 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