{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:36:46Z","timestamp":1788305806220,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,6,21]],"date-time":"2016-06-21T00:00:00Z","timestamp":1466467200000},"content-version":"vor","delay-in-days":51,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Science Funding of China","award":["81370099"],"award-info":[{"award-number":["81370099"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate whether Bi\u2010level positive airway pressure (BiPAP), compared with nasal continuous positive airway pressure (CPAP), is a more effective therapeutic strategy in preterm infants \u226432 weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All inborn infants between 26<jats:sup>+1<\/jats:sup> and 32<jats:sup>+6<\/jats:sup> weeks' gestation, admitted to the neonatal intensive care unit (NICU ) of Tongji Medical Hospital between 1 January, 2010 and 31 December, 2011 (the 2010\u20132011 cohort or CPAP cohort) and between 1 January, 2012 and 31 December, 2013 (the 2012\u20132013 cohort or BiPAP cohort), were retrospectively identified. The primary outcome was intubation in infants\u2009&lt;\u200972 h of age; secondary outcomes were mortality and the incidence of bronchopulmonary dysplasia (BPD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 213 in the 2010\u20132011 cohort and 243 infants in the 2012\u20132013 cohort. There were fewer infants intubated within the first 72 h of age in the 2012\u20132013 cohort than in the 2010\u20132011 cohort (15% vs. 23%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). Of the infants who received some form of positive airway pressure, 12\/94 (13%) of infants on BiPAP versus 23\/74 (31%) on CPAP were subsequently intubated (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). There was no difference in the incidence of moderate and severe BPD between the two groups (7% vs. 8%, <jats:italic>P<\/jats:italic>=0.52).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this retrospective cohort study, we found BiPAP, compared with CPAP, reduced the need for intubation within the first 72 h of age.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.13175","type":"journal-article","created":{"date-parts":[[2016,6,23]],"date-time":"2016-06-23T17:00:48Z","timestamp":1466701248000},"page":"493-498","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Nasal bi\u2010level positive airway pressure (BiPAP) versus nasal continuous positive airway pressure (CPAP) in preterm infants \u226432\u2009weeks: A retrospective cohort study"],"prefix":"10.1111","volume":"52","author":[{"given":"Zhi\u2010Hui","family":"Rong","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Bin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao\u2010Huan","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li\u2010Wen","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6,21]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/pir.33-6-255"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-1826"},{"key":"e_1_2_9_4_1","first-page":"1045","article-title":"Noninvasive positive pressure ventilation or conventional mechanical ventilation for neonatal continuous positive airway pressure failure","volume":"5","author":"Badiee Z","year":"2014","journal-title":"Int. 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