{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:30:00Z","timestamp":1791412200357,"version":"4.3.3"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,9,27]],"date-time":"2016-09-27T00:00:00Z","timestamp":1474934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2017,2]]},"abstract":"Aim<\/jats:title>A prospective observational study was conducted to estimate the prevalence of oropharyngeal carriage of Kingella kingae<\/jats:italic> in healthy Australian pre\u2010school children.<\/jats:p><\/jats:sec>Methods<\/jats:title>Screening for carriage of K. kingae<\/jats:italic> as well as Streptococcus pyogenes<\/jats:italic>, Streptococcus pneumoniae<\/jats:italic>, Streptococcus agalactiae<\/jats:italic>, Staphylococcus aureus<\/jats:italic>, Haemophilus influenzae<\/jats:italic>, and K. kingae<\/jats:italic> was undertaken using a single bacterial throat swab taken from well children aged 6 months to 4 years. Standard laboratory procedures were used for culture and identification of organisms.<\/jats:p><\/jats:sec>Results<\/jats:title>One hundred children were enrolled between October and December 2014 at the Children's Hospital at Westmead. Median age was 24.0\u2009months (range 6.1\u201348.8\u2009months); 52 children were male and 36 attended day\u2010care facilities. Forty\u2010one children had siblings aged less than 5 years and 67 children had siblings of any age. K. kingae<\/jats:italic> oropharyngeal carriage was not detected in any of the children. Rates of carriage of other organisms were: 30% S. aureus<\/jats:italic>, 21% H. influenzae<\/jats:italic>, 2% S. pneumoniae<\/jats:italic> and 2% S. pyogenes<\/jats:italic>. Thirty\u2010eight children were colonised with Kingella denitrificans<\/jats:italic>.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Our results suggest that prevalence of K. kingae<\/jats:italic> carriage in pre\u2010school children in Sydney is very low and support local and national guidelines that recommend flucloxacillin as empiric first\u2010line therapy for children with osteoarticular infections. Studies conducted over the winter months and in other Australian centres could help answer outstanding questions regarding differences in carriage rates of K. kingae<\/jats:italic> in children.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.13337","type":"journal-article","created":{"date-parts":[[2016,9,27]],"date-time":"2016-09-27T12:03:07Z","timestamp":1474977787000},"page":"170-172","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Low prevalence of Kingella kingae<\/i> carriage in children aged 6\u201348 months in Sydney, Australia"],"prefix":"10.1111","volume":"53","author":[{"given":"Ameneh","family":"Khatami","sequence":"first","affiliation":[{"name":"Department of Microbiology and Infectious Diseases The Children's Hospital at Westmead Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Braden RL","family":"Rivers","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Infectious Diseases The Children's Hospital at Westmead Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander C","family":"Outhred","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Infectious Diseases The Children's Hospital at Westmead Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison M","family":"Kesson","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Infectious Diseases The Children's Hospital at Westmead Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,9,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181d57a6c"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31825d3419"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2012.03799.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3182755779"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199508000-00005"},{"key":"e_1_2_9_7_1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1093\/jpids\/pit003","article-title":"Age\u2010dependent carriage of Kingella kingae in young children and turnover of colonizing strains","volume":"3","author":"Amit U","year":"2014","journal-title":"J. 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