{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:25:38Z","timestamp":1759335938277},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,10,4]],"date-time":"2016-10-04T00:00:00Z","timestamp":1475539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To analyse the associations between childcare centres and infectious morbidity and resource consumption.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cohort study from birth to 2\u2009years. Outcome variable: number and types of infections, drug consumption and medical visits. Exposure variable: attending or not attending a childcare centre. School age: 6\u201312, &gt;12\u201318, &gt;18\u201324\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The initial cohort comprised 445 children, and the final cohort comprised 419 children.<\/jats:p><jats:p>The mean number of recurrent infections and wheezing was higher in children attending childcare centres in all age groups with significant differences. Recurrent acute otitis media was observed in the 12\u2010 to 18\u2010month group with an odds ratio of 6.04 (95% confidence interval, 1.3\u201327.6; <jats:italic>P<\/jats:italic>\u2009=\u20090.001) in the children attending childcare centres. In children older than 6\u2009months, there was greater consumption of antibiotics, inhaled bronchodilators, oral and inhaled corticosteroids and montelukast.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Attending a childcare is associated with an increased frequency of recurrent infections and wheezing, as well as the consumption of antibiotics, bronchodilators, corticosteroids and montelukast.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.13372","type":"journal-article","created":{"date-parts":[[2016,10,12]],"date-time":"2016-10-12T15:03:47Z","timestamp":1476284627000},"page":"116-122","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Infectious morbidity and resource use in children under 2\u2009years old at childcare centres"],"prefix":"10.1111","volume":"53","author":[{"given":"Guadalupe","family":"del Castillo\u2010Aguas","sequence":"first","affiliation":[{"name":"Andalusian Health Service Carihuela Health Centre  M\u00e1laga Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Gallego\u2010Iborra","sequence":"additional","affiliation":[{"name":"Andalusian Health Service Trinidad Health Centre  M\u00e1laga Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Guti\u00e9rrez\u2010Olid","sequence":"additional","affiliation":[{"name":"Andalusian Health Service Delicias Health Centre  M\u00e1laga Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"P\u00e9rez\u2010Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Fimabis  M\u00e1laga Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ginesa","family":"Moreno\u2010Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Andalusian Health Service Puerto de la Torre Health Centre  M\u00e1laga Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juana M","family":"Ledesma\u2010Albarr\u00e1n","sequence":"additional","affiliation":[{"name":"Andalusian Health Service Delicias Health Centre  M\u00e1laga Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,10,4]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1135-57272007000200003"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/02813439008994942"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1990.tb11563.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1111\/j.1651-2227.2000.tb00744.x","article-title":"Socio\u2010economic differences in daycare arrangements and use of medical care and antibiotics in Swedish preschool children","volume":"89","author":"Hjern A","year":"2007","journal-title":"Acta Paediatr."},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.111.4.e371"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2007.00323.x"},{"key":"e_1_2_9_8_1","first-page":"128","article-title":"Acute respiratory infections in children of day care center: Characteristics and costs","volume":"23","author":"Delpiano ML","year":"2006","journal-title":"Rev. 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