{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T06:16:20Z","timestamp":1789193780086,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T00:00:00Z","timestamp":1478736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Murdoch Children's Research Institute (Career Development Award)"},{"name":"Royal Australasian College of Surgeons (Senior Lecturer Fellowship)"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of the study is to investigate the effectiveness of Peristeen retrograde continence enema (<jats:styled-content style=\"fixed-case\">RCE<\/jats:styled-content>) in the management of faecal incontinence in children with spina bifida.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We identified a homogenous group of spina bifida patients in whom <jats:styled-content style=\"fixed-case\">RCE<\/jats:styled-content> was initiated (Jan 2006\u2013July 2013). Confidential assessments included (i) Fecal Incontinence Quality Of Life (<jats:styled-content style=\"fixed-case\">FIQOL<\/jats:styled-content>), (ii) St Marks Faecal Incontinence score, (iii) Cleveland Clinic Constipation score and (iv) Neurogenic Bowel Dysfunction score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 20 patients, 11 (mean age 14.5 \u00b1 5.3 years) were male. Of 20 patients, nine were still using <jats:styled-content style=\"fixed-case\">RCE<\/jats:styled-content> (mean follow\u2010up 4.1 years). Three patients ceased <jats:styled-content style=\"fixed-case\">RCE<\/jats:styled-content> within 10 days, six after 4\u201312 months and two after 36\u201348 months. Reasons for cessation included balloon difficulties (<jats:italic>n<\/jats:italic> = 4), procedure deemed too difficult (<jats:italic>n<\/jats:italic> = 4) and pain (<jats:italic>n<\/jats:italic> = 3).<\/jats:p><jats:p>There were no differences between the groups in length of training time for technique, instillate fluid\/volume used and time taken to perform <jats:styled-content style=\"fixed-case\">RCE<\/jats:styled-content>. There were no differences between the groups for quality of life, faecal incontinence or constipation scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We demonstrated a high rate of cessation with <jats:styled-content style=\"fixed-case\">RCE<\/jats:styled-content> in patients with spina bifida. This could not be explained by associated conditions, or by enema\u2010related parameters. One possible explanation is the lack of ongoing outpatient support for the children and their families.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.13408","type":"journal-article","created":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T16:09:03Z","timestamp":1478794143000},"page":"386-390","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Retrograde continence enema in children with spina bifida: Not as effective as first thought"],"prefix":"10.1111","volume":"53","author":[{"given":"Sebastian K","family":"King","sequence":"first","affiliation":[{"name":"Department of Paediatric Surgery The Royal Children's Hospital  Melbourne Victoria Australia"},{"name":"Surgical Research Laboratory Murdoch Childrens Research Institute  Melbourne Victoria Australia"},{"name":"Department of Paediatrics University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lefteris","family":"Stathopoulos","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery The Royal Children's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loreto","family":"Pinnuck","sequence":"additional","affiliation":[{"name":"Department of Stoma Therapy Monash Medical Centre  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judy","family":"Wells","sequence":"additional","affiliation":[{"name":"Department of Stoma Therapy, and The Royal Children's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Hutson","sequence":"additional","affiliation":[{"name":"Surgical Research Laboratory Murdoch Childrens Research Institute  Melbourne Victoria Australia"},{"name":"Department of Paediatrics University of Melbourne  Melbourne Victoria Australia"},{"name":"Department of Urology The Royal Children's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Heloury","sequence":"additional","affiliation":[{"name":"Department of Urology The Royal Children's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3101705"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004703-198604000-00007"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2013.08.006"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.043620"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)92834-5"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(93)90505-F"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)67155-6"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(97)90470-X"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(96)90490-X"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2005.08.011"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(87)80345-7"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2010.5"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.09.007"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2013.11.036"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2009.07.004"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02237236"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.44.1.77"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02056950"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3101887"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.03.103"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64613-7"},{"key":"e_1_2_9_23_1","article-title":"Management of faecal incontinence and constipation in adults with central neurological diseases","author":"Coggrave M","journal-title":"Cochrane Database Syst. 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