{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T18:56:17Z","timestamp":1785869777270,"version":"3.56.0"},"reference-count":39,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,4,20]],"date-time":"2017-04-20T00:00:00Z","timestamp":1492646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Upper gastrointestinal (<jats:styled-content style=\"fixed-case\">UGI<\/jats:styled-content>) contrast study is the preferred radiological investigation to diagnose malrotation of intestine. We aimed to review the role of <jats:styled-content style=\"fixed-case\">UGI<\/jats:styled-content> contrast in neonates (term and preterm) who were clinically suspected to have malrotation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study included a retrospective review of medical charts and radiology reports.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 164 newborn infants underwent <jats:styled-content style=\"fixed-case\">UGI<\/jats:styled-content> contrast study to rule out malrotation during the study period (2006\u20132015). Median gestational age at the time of presentation was 38 weeks (interquartile range: 35.5\u201339.6\u2009weeks). Median age for clinical presentation was day 2 of life (interquartile range: 2\u20135 days). Out of the 164 contrast studies, 112 were normal, whereas 52 were reported to have malrotation. Of those 52 infants, 47 were confirmed to have malrotation on surgery (positive predictive value: 90). Of the 112 infants with normal <jats:styled-content style=\"fixed-case\">UGI<\/jats:styled-content> contrasts, nine infants underwent laparotomy for ongoing clinical symptoms out of which four infants were diagnosed to have malrotation on laparotomy. There were 22 infants born at gestational age &lt;32\u2009weeks, who underwent <jats:styled-content style=\"fixed-case\">UGI<\/jats:styled-content> contrast studies to rule out malrotation. Their clinical symptoms were similar to necrotising enterocolitis. Of 22 preterm contrast studies, six were reported to have malrotation; of these, five had surgically confirmed malrotation. No complications related to the contrast study were noted in both term and preterm infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Current study reaffirms the role of <jats:styled-content style=\"fixed-case\">UGI<\/jats:styled-content> contrast study as the investigation of choice for diagnosis of malrotation, in both term and preterm infants. <jats:styled-content style=\"fixed-case\">UGI<\/jats:styled-content> contrast is safe and well tolerated even in preterm infants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.13515","type":"journal-article","created":{"date-parts":[[2017,4,20]],"date-time":"2017-04-20T10:38:41Z","timestamp":1492684721000},"page":"644-649","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Role of upper gastrointestinal contrast studies for suspected malrotation in neonatal population"],"prefix":"10.1111","volume":"53","author":[{"given":"Suresh","family":"Birajdar","sequence":"first","affiliation":[{"name":"Department of Neonatology Princess Margaret Hospital for Children  Perth Western Australia Australia"},{"name":"Department of Neonatology King Edward Memorial Hospital for Women  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shripada C","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Neonatology Princess Margaret Hospital for Children  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona","family":"Bettenay","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging Princess Margaret Hospital for Children  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01658699"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2004.04.024"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02047549"},{"key":"e_1_2_8_5_1","first-page":"1","article-title":"Surveillance for and comparison of birth defect prevalences in two geographic areas: United States, 1983\u201388","volume":"42","author":"Schulman J","year":"1993","journal-title":"Morb. 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